ChemicalBook > CAS DataBase List > 15(R)-ILOPROST

15(R)-ILOPROST

Product Name
15(R)-ILOPROST
CAS No.
85026-51-3
Chemical Name
15(R)-ILOPROST
Synonyms
15(R)-ILOPROST;HIFJCPQKFCZDDL-GAGQTBDJSA-N;15(R)-IloprostQ: What is 15(R)-Iloprost Q: What is the CAS Number of 15(R)-Iloprost;6,9ALPHA-METHYLENE-11ALPHA,15R-DIHYDROXY-16-METHYL-PROSTA-5E,13E-DIEN-18-YN-1-OIC ACID;Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)- (9CI)
CBNumber
CB3708080
Molecular Formula
C22H32O4
Formula Weight
360.49
MOL File
85026-51-3.mol
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15(R)-ILOPROST Property

solubility 
DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
10043
Product name
15(R)-Iloprost
Purity
≥97%
Packaging
500μg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
10043
Product name
15(R)-Iloprost
Purity
≥97%
Packaging
1mg
Price
$206
Updated
2024/03/01
Cayman Chemical
Product number
10043
Product name
15(R)-Iloprost
Purity
≥97%
Packaging
5mg
Price
$856
Updated
2024/03/01
Cayman Chemical
Product number
10043
Product name
15(R)-Iloprost
Purity
≥97%
Packaging
10mg
Price
$1495
Updated
2024/03/01
AK Scientific
Product number
1212AH
Product name
15(R)-Iloprost
Packaging
10mg
Price
$1763
Updated
2021/12/16
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15(R)-ILOPROST Chemical Properties,Usage,Production

Description

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP receptors with a Ki of 11 nM. 15(R)-Iloprost is the “unnatural” or inverted C-15 epimer of iloprost. This transformation frequently attenuates the biological agonist activity of prostaglandin analogs by several orders of magnitude. There are no literature reports of the biological activity of 15(R)-iloprost.

Uses

15(R)-Iloprost is the unnatural or inverted C-15 epimer of lloprost (HY-A0096)[1].

References

[1] W J van der Giessen, et al. The effect of the stable prostacyclin analogue ZK 36374 on experimental coronary thrombosis in the pig. Thromb Res. 1984 Oct 1;36(1):45-51. DOI:10.1016/0049-3848(84)90375-x

15(R)-ILOPROST Preparation Products And Raw materials

Raw materials

Preparation Products

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15(R)-ILOPROST Suppliers

China 23 India 1 Switzerland 1 United States 1 Global 26
AXXORA, LLC
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.com
Country
Switzerland
ProdList
1104
Advantage
80

85026-51-3, 15(R)-ILOPROSTRelated Search:

Iloprost ILOPROST 15(R)-ILOPROST

  • 6,9ALPHA-METHYLENE-11ALPHA,15R-DIHYDROXY-16-METHYL-PROSTA-5E,13E-DIEN-18-YN-1-OIC ACID
  • 15(R)-ILOPROST
  • HIFJCPQKFCZDDL-GAGQTBDJSA-N
  • Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)- (9CI)
  • 15(R)-IloprostQ: What is 15(R)-Iloprost Q: What is the CAS Number of 15(R)-Iloprost
  • 85026-51-3