ChemicalBook > CAS DataBase List > 4-(Difluoromethoxy)nitrobenzene

4-(Difluoromethoxy)nitrobenzene

Product Name
4-(Difluoromethoxy)nitrobenzene
CAS No.
1544-86-1
Chemical Name
4-(Difluoromethoxy)nitrobenzene
Synonyms
BUTTPARK 45\10-48;α,α-Difluoro-p-nitroanisole;Anisole,α,α-difluoro-p-nitro-;4-(DIFLUOROMETHOXY)NITROBENZENE;p-Nitrophenyldifluoromethylether;Difluoromethyl4-nitrophenylether;1-(DIFLUOROMETHOXY)-4-NITROBENZENE;4-(Difluoromethoxy)nitrobenzene98%;4-(Difluoromethoxy)nitrobenzen, 98%;4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE
CBNumber
CB3714535
Molecular Formula
C7H5F2NO3
Formula Weight
189.12
MOL File
1544-86-1.mol
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4-(Difluoromethoxy)nitrobenzene Property

Melting point:
37-40 °C (lit.)
Boiling point:
108 °C
Density 
1.384±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
2-8°C
form 
powder to lump
color 
Light yellow to Brown to Dark green
FreezingPoint 
31.0 to 34.0 ℃
CAS DataBase Reference
1544-86-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37
RIDADR 
3276
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29049090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S39811
Product name
1-DIFLUOROMETHOXY-4-NITRO-BENZENE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
S39811
Product name
1-DIFLUOROMETHOXY-4-NITRO-BENZENE
Purity
Aldrich
Packaging
100mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
D2601
Product name
4-(Difluoromethoxy)nitrobenzene
Packaging
5g
Price
$52
Updated
2025/07/31
TRC
Product number
D452243
Product name
4-(Difluoromethoxy)nitrobenzene
Packaging
500mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
005997
Product name
4-(Difluoromethoxy)nitrobenzene
Purity
98%
Packaging
1g
Price
$10
Updated
2021/12/16
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4-(Difluoromethoxy)nitrobenzene Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Crystal.

Uses

4-(Difluoromethoxy)nitrobenzene is an industrial chemical that can be used to make 4-fluoro-3-pyridinol (F3P), a compound that has potential as a new drug for the treatment of cancer. The synthesis of F3P begins with the reaction of 4-(difluoromethoxy)nitrobenzene and potassium hydroxide in methanol, which yields 4-fluoro-3-hydroxypyridine. This product is then reacted with ammonia gas and pyridine to yield F3P. The final step involves heating the product at high temperature with nitric acid, which yields nitrobenztriazole.

General Description

4-(Difluoromethoxy)nitrobenzene (1-(difluoromethoxy)-4-nitrobenzene) can be synthesized by reacting 4-nitrophenol with KOH, water and methanol.

4-(Difluoromethoxy)nitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Difluoromethoxy)nitrobenzene Suppliers

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View Lastest Price from 4-(Difluoromethoxy)nitrobenzene manufacturers

henan kanbei chemical co.,ltd
Product
4-(DIFLUOROMETHOXY)NITROBENZENE 1544-86-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2022-09-19
Honest Joy Holdings Limited
Product
4-(Difluoromethoxy)nitrobenzene 1544-86-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
4-(DIFLUOROMETHOXY)NITROBENZENE 1544-86-1
Price
US $7.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
JD724
Release date
2019-09-02

1544-86-1, 4-(Difluoromethoxy)nitrobenzeneRelated Search:

2,2-DIFLUORO-5-NITRO-1,3-BENZODIOXOLE 4-(Difluoromethoxy)nitrobenzene 2,4-Dinitro-1-(trifluoromethoxy)benzene 2-(DIFLUOROMETHOXY)-5-NITROANILINE 4-(Trifluoromethoxy)nitrobenzene 2-BROMO-4-NITRO(TRIFLUOROMETHOXY)BENZENE 4-(1,1,2,2-TETRAFLUOROETHOXY)NITROBENZENE 2-(DIFLUOROMETHOXY)NITROBENZENE,2-(Difluoromethoxy)nitrobenzene 97%,2-(Difluoromethoxy)nitrobenzene97% 3-(DIFLUOROMETHOXY)NITROBENZENE (DIFLUOROMETHOXY)BENZENE Anisole 2-TETRAFLUOROETHOXY-5-NITROTOLUENE 4-(BROMODIFLUOROMETHOXY)NITROBENZENE 2-(DIFLUOROMETHOXY)-5-NITROBENZALDEHYDE 1-(CHLORO-DIFLUORO-METHOXY)-4-NITRO-BENZENE 1-NITRO-4-TRIFLUOROMETHOXY-2-TRIFLUOROMETHYL-BENZENE 2,4-DINITRO-1-(1,1,2,2-TETRAFLUOROETHOXY)BENZENE RARECHEM AL BE 0471

  • BUTTPARK 45\10-48
  • Anisole,α,α-difluoro-p-nitro-
  • Benzene,1-(difluoromethoxy)-4-nitro-
  • Difluoromethyl4-nitrophenylether
  • p-Nitrophenyldifluoromethylether
  • 1-(DIFLUOROMETHOXY)-4-NITROBENZENE
  • 4-(DIFLUOROMETHOXY)NITROBENZENE
  • 4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE
  • α,α-Difluoro-p-nitroanisole
  • 4-(Difluoromethoxy)nitrobenzen, 98%
  • 4-(Difluoromethoxy)nitrobenzene98%
  • Difluoromethyl 4-nitrophenyl ether, alpha,alpha-Difluoro-4-nitroanisole, 1-(Difluoromethoxy)-4-nitrobenzene
  • alpha,alpha-Difluoro-p-nitroanisole
  • 1544-86-1
  • F2CHOC6H4NO2
  • Building Blocks
  • Nitro Compounds
  • Organic Building Blocks
  • Nitrogen Compounds
  • Building Blocks
  • Chemical Synthesis
  • Nitro Compounds
  • Nitrogen Compounds
  • Organic Building Blocks