ChemicalBook > CAS DataBase List > 6-THIOGUANOSINE

6-THIOGUANOSINE

Product Name
6-THIOGUANOSINE
CAS No.
85-31-4
Chemical Name
6-THIOGUANOSINE
Synonyms
TGR;TRXR3;TXNRD3;sri759;sk18615;nsc-29422;thioguanosine;6-THIOGUANOSINE;6-thio-guanosin;Guanosine, 6-thio-
CBNumber
CB3722231
Molecular Formula
C10H13N5O4S
Formula Weight
299.31
MOL File
85-31-4.mol
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6-THIOGUANOSINE Property

Melting point:
230-231°C
Boiling point:
756.9±70.0 °C(Predicted)
Density 
2.18
refractive index 
1.6460 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka
13.21±0.70(Predicted)
CAS DataBase Reference
85-31-4(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
RTECS 
UP0200000
HS Code 
29349990
Toxicity
LD50 intraperitoneal in mouse: 156mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
296445
Product name
6-Thioguanosine
Packaging
100mg
Price
$305
Updated
2021/12/16
Biosynth Carbosynth
Product number
NT04480
Product name
6-Thioguanosine
Packaging
1g
Price
$400
Updated
2021/12/16
Matrix Scientific
Product number
099736
Product name
6-Thioguanosine
Purity
95+%
Packaging
250mg
Price
$515
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0002382
Product name
6-THIOGUANOSINE
Purity
95.00%
Packaging
0.25G
Price
$786
Updated
2021/12/16
Matrix Scientific
Product number
099736
Product name
6-Thioguanosine
Purity
95+%
Packaging
1g
Price
$1143
Updated
2021/12/16
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6-THIOGUANOSINE Chemical Properties,Usage,Production

Chemical Properties

Tan Powder

Uses

antineoplastic

Definition

ChEBI: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-3H-purine-6-thione is a purine nucleoside.

Purification Methods

Thioguanosine is crystallised (as hemihydrate) from hot H2O (charcoal) and cooled slowly to give tapered prisms. It also crystallises by dissolving in dilute NH3 and acidifying with acetic acid, and then recrystallising from H2O. UV: (pH 4-6) max at 257nm ( 8,820) and 342nm ( 24,800), and (pH 10.4-12.0) max at 252nm ( 14,700) and 319.5nm ( 21,000). [Fox et al. J Am Chem Soc 80 1667 1958, Beilstein 26 III/IV 3927.]

6-THIOGUANOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-THIOGUANOSINE Suppliers

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85-31-4, 6-THIOGUANOSINERelated Search:

6-THIOGUANOSINE 6-Thioguanosine hydrate 6-MERCAPTOPURINE RIBOSIDE Purine 2-Aminopurine Guanine 2-Aminopurine riboside 6-thioguanosine 5'-triphosphate 1-METHYL-6-THIOGUANOSINE 8-(2-AMINOETHYL) THIOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER, IMMOBILIZED ON AGAROSE GEL sulfinosine 2-AMINO-6-MERCAPTO-9-(2',3',5'-TRI-O-ACETYL-B-RIBOFURANOSYL)PURINE 2-AMINO-6-CHLORO-[(4-METHYLPHENYL)THIO]-9-(2',3',5'-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)PURINE 7-METHYL-6-THIOGUANOSINE S-(2-HYDROXY-5-NITROBENZYL)-6-THIOGUANOSINE S-(4-NITROBENZYL)-6-THIOGUANOSINE (NBTG) POTENT ADENOSINE TRAN,S-(4-NITROBENZYL)-6-THIOGUANOSINE,S-(P-NITROBENZYL)-6-THIOGUANOSINE 8-(2-AMINOETHYL) THIOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE, IMMOBILIZED ON AGAROSE GEL 2'-deoxy-6-thioguanosine 5'-triphosphate

  • Guanosine, 6-thio-
  • ANTI-TXNRD3 (CENTER) antibody produced in rabbit
  • Thioredoxin and glutathione reductase
  • Thioredoxin reductase 3
  • TRXR3
  • TXNRD3
  • 2-Amino-6-mercaptopurine-9-D-riboside
  • 2-AMINO-6-MERCAPTOPURINE RIBOSIDE
  • 6-MERCAPTOGUANOSINE
  • 6-MERCAPTO-2-AMINOPURINE RIBOSIDE
  • 6-THIOGUANOSINE
  • 2-amino-6-mercaptopurin-9-ylriboside
  • 2-Amino-6-mercapto-9-β-D-ribofuranosylpurine
  • 2-Amino-6-mercapto-9-(b-D-ribofuranosyl)purinehydrate
  • 2-Amino-6-mercaptopurine riboside, 6-Mercapto-2-aminopurine riboside, 6-Thioguanosine
  • 2-Amino-9-β-D-ribofuranosyl-9H-purine-6-thiol
  • TGR
  • 2-Amino-6-mercapto-9-(β-D-ribofuranosyl)purine hydrate
  • 2-amino-1,9-dihydro-9-beta-d-ribofuranosyl-6h-purine-6-thion
  • 2-amino-6-mercapto-9(beta-d-ribofuranosyl)purine
  • 2-amino-6-mercaptopurineribonucleoside
  • 2-amino-9-(beta-d-ribofuranosyl)purine-6-thiol
  • 2-amino-9-beta-d-ribofuranosyl-9h-purine-6-thio
  • 2-amino-9-beta-d-ribofuranosyl-9h-purine-6-thiol
  • 6-thiodeoxyguanosine
  • 6-thioguanineribonucleoside
  • 6-thioguanineriboside
  • 6-thio-guanosin
  • nsc-29422
  • ribosylthioguanine
  • sk18615
  • sri759
  • thioguanineriboside
  • thioguanosine
  • N-(4-iodophenyl)ethanamide
  • 2-AMino-9-β-D-ribofuranosylpurine-6-thione
  • 9-β-D-Ribofuranosylthioguanine
  • 6-THIOGUANOSINE USP/EP/BP
  • 85-31-4
  • C10H13N5O4SH2O
  • C10H13N5O4S
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides
  • Sulfur & Selenium Compounds