Aucubin

Product Name: Aucubin
CAS No.: 479-98-1
Chemical Name: Aucubin
Synonyms: AUCUBIN;Rhimantin;Nsc407293;Aucubosid;AUCUBOSIDE;Aids031379;Rhimanthin;RHINANTHIN;AUCUBIN(P);Aids-031379
CBNumber: CB3739541
Molecular Formula: C15H22O9
Formula Weight: 346.33
MOL File: 479-98-1.mol

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Aucubin Property

Melting point:: 181°
alpha: D21 -163.1° (c = 1.6)
Boiling point:: 669.0±55.0 °C(Predicted)
Density: 1.61±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form: Solid
pka: 12.80±0.70(Predicted)
color: White
optical activity: -16518 (H2O)
BRN: 50340
InChI: InChI=1/C15H22O9/c16-4-6-3-8(18)7-1-2-22-14(10(6)7)24-15-13(21)12(20)11(19)9(5-17)23-15/h1-3,7-21H,4-5H2/t7-,8+,9+,10+,11+,12-,13+,14-,15-/s3
InChIKey: RJWJHRPNHPHBRN-FKVJWERZSA-N
SMILES: [C@@]12([H])C(CO)=C[C@@H](O)[C@]1([H])C=CO[C@H]2O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O |&1:0,6,8,13,15,16,18,19,21,r|
LogP: -4.103 (est)
CAS DataBase Reference: 479-98-1(CAS DataBase Reference)

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Safety

Risk Statements: 22
Safety Statements: 22-45
WGK Germany: 3
F: 10-23

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 55561
Product name: Aucubin
Purity: analytical standard
Packaging: 5mg
Price: $77.2
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHL89163
Product name: Aucubin
Purity: phyproof? Reference Substance
Packaging: 20MG
Price: $311
Updated: 2025/07/31

Sigma-Aldrich

Product number: 55561
Product name: Aucubin
Purity: analytical standard
Packaging: 25mg
Price: $321
Updated: 2025/07/31

Sigma-Aldrich

Product number: 00090590
Product name: Aucubin
Purity: primary pharmaceutical reference standard
Packaging: 25mg
Price: $610
Updated: 2025/07/31

TCI Chemical

Product number: A3604
Product name: Aucubin
Packaging: 100MG
Price: $345
Updated: 2025/07/31

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Aucubin Chemical Properties,Usage,Production

Chemical Properties

Aucubin, bitter in taste, easily soluble in water, ethanol, methanol, insoluble in chloroform, ether, petroleum ether and other solvents. It is a kind of iridoid compound that widely exists in many plant species in nature.

Uses

Aucubine 5-Acetatea is an impurity of Aucubine (A794730). Aucubine shows antioxidant and protective effects for the liver and kidney organs, shown in mice with induced diabetes.

Definition

ChEBI: Aucubin is an organic molecular entity. It has a role as a metabolite.

Mechanism of action

Aucubin can be used to clear dampness and heat, facilitate urination, relieving pain, reduce blood pressure and protecting liver. It can promote the regeneration of stem cells, significantly inhibit the replication of hepatitis B virus DNA.

in vivo

Aucubin (5 mg/kg; i.p. for 15 d) has antioxidant and pancreas-protective effects on rats with streptozotocin-induced diabetes^[1].
Aucubin (40-200 mg/kg; a single i.p.) exhibits significant protective activity against α-amanitin intoxication in mice^[5].
Aucubin (5 mg/kg/day; i.p. for 21 d) decreases the breathing frequency, increases the lung dynamic compliance, alleviates lung parenchymal fibrotic changes, and reduces the intrapulmonary collagen disposition and inflammatory injury of BLM-stimulated mice^[6].

Animal Model:	Male Wistar rats (200-230 g) induced diabetes by a injection of streptozotocin^[1]
Dosage:	5 mg/kg
Administration:	I.p. twice daily for the first 5 days, followed by single injections daily for the last 10 days
Result:	Increased the body weight of streptozotocin-diabetic rats. Lowered the blood glucose level. Decreased the level of lipid peroxidation and increased the activities of antioxidant enzymes. Increased in insulin immunoreactivity and the number of immunoreactive β cells compared with untreated diabetic rats.

Aucubin Preparation Products And Raw materials

Raw materials

Preparation Products

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Aucubin Suppliers

China 270 France 2 Germany 6 India 3 Japan 1 Switzerland 1 United Kingdom 8 United States 29 USA 1 Global 321

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5167
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Chengdu Biopurify Ltd.

Tel: 28-82633860 18982077548
Email: cwb1@biopurify.cn
Country: China
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
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Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
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Sichuan Kulinan Technology Co., Ltd

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Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
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Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
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Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
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ProdList: 6387
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BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
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ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
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View Lastest Price from Aucubin manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Aucubin 479-98-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: Aucubin 479-98-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

Career Henan Chemical Co

Product: Aucubin 479-98-1
Price: US $1.00/kg
Min. Order: 1 mg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-25

479-98-1, AucubinRelated Search:

CHLOROPHOSPHONAZO III Catalpol Geniposide std. Paclitaxel Arctiin Verbascoside Salidroside PINORESINOL DIGLUCOSIDE(P)(PLEASE CALL) AGRIMOPHOL Picroside II ACETALDEHYDE ETHYL CIS-3-HEXENYL ACETAL Yuheiside 3,4-DIHYDRO-2-METHOXY-4-METHYL-2H-PYRAN (E)-2-METHYL-HEPTA-2,6-DIEN-1-OL cyclopent-2-en-1-ol [(1S)-1β,4aβ,5,7aβ-Tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl]β-D-glucopyranoside Aucubin Aucubin Impurity 1

AUCUBIN

AUCUBOSIDE

B-D-GLUCOPYRANOSIDE, (1S,4AR,5S,7AS)-1,4A,5,7A-TETRAHYDRO-5-HYDROXY-7-(HYDROXYMETHYL)CYCLOPENTA[C]PYRAN-1-YL

(2S,3R,4S,5S,6R)-2-((1S,4Ar,5R,7as)-5-hydroxy-7-hydroxymethyl-1,4A,5,7A-tetrahydro-cyclopenta[C]pyran-1-yloxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol

Aids031379

Aids-031379

Nsc407293

b-D-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl, [1S-(1a,4a,5a,7a)]

Rhimantin

1S-(1alpha,4aalpha,5alpha,7aalpha)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside

6-Epiaucubin

[(1S)-1,4aα,5,7aα-Tetrahydro-5α-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1α-yl]β-D-glucopyranoside

Aucubigenin 1-O-β-D-glucopyranoside

Rhimanthin

Aucubin, 98%, from Eucommia ulmoides Oliver

RHINANTHIN

1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside

[1S-(1alpha,4aalpha,5alpha,7aalpha)]-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside

(2S,3R,4S,5S,6R)-2-{[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxyMethyl)-1H,4aH,5H,7aH-cyclopenta[c]pyran-1-yl]oxy}-6-(hydroxyMethyl)oxane-3,4,5-triol

Aucubosid

(1S,4aR,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl β-D-glucopyranoside

AUCUBINB-D-GLUCOPYRANOSIDE, (1S,4AR,5S,7AS)-1,4A,5,7A-TETRAHYDRO-5-HYDROXY-7-(HYDROXYMETHYL)CYCLOPENTA[C]PYRAN-1-YL,

Aucubin std.

AUCUBIN(P)

AUCUBIN hplc

AUCUBIN WITH HPLC

[c]pyran-1-yl

tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta

β-D-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-

(2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Aucubin Standard

β-D-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl

Aucubin USP/EP/BP

1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c...

Aucubin 479-98-1

(2S,3R,4S,5S,6R)-2-(((1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

b-D-Glucopyranoside,(1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl

Aucubine-RM

Aucubin, 10 mM in DMSO

479-98-1

C15H22O9

AR to AZ

Analytical Standards

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chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Iridoids

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