2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

Product Name: 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
CAS No.: 62732-44-9
Chemical Name: 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
Synonyms: Takinocrine;Brn 0475930;MFCD11052605;AKOS MSC-0106;AURORA KA-7699;Unii-cv71vtp0vn;CBI-BB ZERO/005050;Ipidacrine, 10 mM in DMSO;8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine;2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-
CBNumber: CB3740985
Molecular Formula: C12H16N2
Formula Weight: 188.27
MOL File: 62732-44-9.mol

More

Less

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Property

Melting point:: 202-203 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point:: 368.0±42.0 °C(Predicted)
Density: 1.170±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 25 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form: A solid
pka: 10.88±0.20(Predicted)
color: White to off-white

More

Less

Safety

Hazard Codes: Xi
Hazard Note: Irritant

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

TRC

Product number: I739330
Product name: Ipidacrine
Packaging: 1g
Price: $870
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 46880
Product name: Ipidacrine
Packaging: 10g
Price: $2000
Updated: 2021/12/16

Matrix Scientific

Product number: 134023
Product name: 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
Purity: 95%+
Packaging: 2.500g
Price: $324
Updated: 2021/12/16

Matrix Scientific

Product number: 134023
Product name: 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
Purity: 95%+
Packaging: 100mg
Price: $58
Updated: 2021/12/16

Matrix Scientific

Product number: 134023
Product name: 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
Purity: 95%+
Packaging: 500mg
Price: $112
Updated: 2021/12/16

More

Less

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Chemical Properties,Usage,Production

Uses

Ipidacrine is used in biological studies as a possible treatment of toxic cognitive disorders.

Definition

ChEBI: 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine is an aminoquinoline.

in vivo

Ipidacrine (1 mg/kg, p.o., repeated and a single dose for 5 days) by repeated administration has more potent antiamnesic effects than by single administration in induced by nucleus basalis of meynert (NBM) induced rats^[1].
Ipidacrine (10 mg/kg p.o., a single dose) significantly decreases spontaneous movements, which is more selective as an antiamnesic than either Tacrine (HY-111338) and E-2020 (HY-B0034) in rats^[1].
Ipidacrine (6.7 mg/kg, intragastrically, daily for 14 days) leads to statistically more efficient evolving of intracavernous pressure (ICPmax)/maxipressure (MAP) compared with control group in Streptozotocin (STZ) (HY-13753)-induced diabetic rats^[3].

Animal Model:	Rats^[1]
Dosage:	1 mg/kg
Administration:	p.o., repeated and a single dose for 5 days
Result:	The repeated administration of ipidacrine improved amnesia induced by nucleus basalis of meynert (NBM) lesions in the passive avoidance task in rats.

Animal Model:	Rats^[1]
Dosage:	3, 10, 30 mg/kg
Administration:	p.o., a single dose
Result:	Decreased pupil size and increased salivation at 3 mg/kg, decreased spontaneous movements at 10 mg/kg and decreased body temperature and induced tremor at 30 mg/kg in rats.

Animal Model:	Rats with streptozotocin (STZ) (HY-13753) induced diabetes mellitus-induced erectile dysfunction (DMED)^[1]
Dosage:	6.7 mg/kg
Administration:	crushed, suspended in 1% starch solution and administered intragastrically daily for 14 days
Result:	Ipidacrine was as effective as sildenafil and could significantly improve DMED symptoms.

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Suppliers

Austria 1 China 43 Germany 2 India 1 Russia 3 United Kingdom 4 United States 12 USA 1 Global 67

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16684
Advantage: 50

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

More

Less

View Lastest Price from 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE manufacturers

Career Henan Chemical Co

Product: 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE 62732-44-9
Price: US $1000.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10KG
Release date: 2018-08-04

62732-44-9, 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINERelated Search:

ipilimumab 2,6-DIMETHYL-PYRIDIN-4-YLAMINE 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate (1:1:1) Cyclopenta[b]pyridine 5,6,7,8-tetrahydro-3-methylquinoline 5,6,7,8-Tetrahydroquinaldine 4-PYRIDINAMINE, 5-ETHYL-2-METHYL- 3,5-dimethylpyridin-4-amine AMIRIDIN 4-Pyridinamine,2,3-dimethyl-(9CI) 2,6-diethylpyridine 3,5-DIETHYL PYRIDINE 5-BUTYL-2-METHYL-PYRIDINE 4-AMINO-2-METHYL-5,6,7,8-TETRAHYDROQUINOLINE 2,6-DIPROPYL PYRIDINE 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE 2,5-diethylpyridine

9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta(b)quinoline monohydrochloride

MFCD11052605

1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine

CBI-BB ZERO/005050

AURORA KA-7699

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

9-AMINO-2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLINE

AKOS MSC-0106

2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate

9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopentaxinolina monohydrate

2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine

Takinocrine

1H-Cyclopenta(B)quinolin-9-amine, 2,3,5,6,7,8-hexahydro-

Brn 0475930

Unii-cv71vtp0vn

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine(SALTDATA: HCl H2O)

8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine

1H-Cyclopenta(b)quinoline, 2,3,5,6,7,8-hexahydro-9-amino-, monohydrochloride

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-ylamine hydrochloride

2,3,5,6,7,8-Hexahydro-9-amino-1H-cyclopenta(b)quinoline hydrochloride

Ipidacrine,inhibit,cholinesterase,nootropic,Inhibitor,Cholinesterase (ChE),Alzheimer disease

Ipidacrine, 10 mM in DMSO

62732-44-9