ChemicalBook > CAS DataBase List > 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

Product Name: 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
CAS No.: 62732-44-9
Chemical Name: 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE
Synonyms: Takinocrine;Brn 0475930;MFCD11052605;AKOS MSC-0106;AURORA KA-7699;Unii-cv71vtp0vn;CBI-BB ZERO/005050;Ipidacrine, 10 mM in DMSO;8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine;2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-
CBNumber: CB3740985
Molecular Formula: C12H16N2
Formula Weight: 188.27
MOL File: 62732-44-9.mol

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2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Property

Melting point:: 202-203 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point:: 368.0±42.0 °C(Predicted)
Density: 1.170±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 25 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
form: A solid
pka: 10.88±0.20(Predicted)
color: White to off-white

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Safety

Hazard Codes: Xi
Hazard Note: Irritant

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: I739330
Product name: Ipidacrine
Packaging: 1g
Price: $870
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 46880
Product name: Ipidacrine
Packaging: 10g
Price: $2000
Updated: 2021/12/16

Matrix Scientific

Product number: 134023
Product name: 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
Purity: 95%+
Packaging: 2.500g
Price: $324
Updated: 2021/12/16

Matrix Scientific

Product number: 134023
Product name: 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
Purity: 95%+
Packaging: 100mg
Price: $58
Updated: 2021/12/16

Matrix Scientific

Product number: 134023
Product name: 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine
Purity: 95%+
Packaging: 500mg
Price: $112
Updated: 2021/12/16

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2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Chemical Properties,Usage,Production

Uses

Ipidacrine is used in biological studies as a possible treatment of toxic cognitive disorders.

Definition

ChEBI: 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine is an aminoquinoline.

in vivo

Ipidacrine (1 mg/kg, p.o., repeated and a single dose for 5 days) by repeated administration has more potent antiamnesic effects than by single administration in induced by nucleus basalis of meynert (NBM) induced rats^[1].
Ipidacrine (10 mg/kg p.o., a single dose) significantly decreases spontaneous movements, which is more selective as an antiamnesic than either Tacrine (HY-111338) and E-2020 (HY-B0034) in rats^[1].
Ipidacrine (6.7 mg/kg, intragastrically, daily for 14 days) leads to statistically more efficient evolving of intracavernous pressure (ICPmax)/maxipressure (MAP) compared with control group in Streptozotocin (STZ) (HY-13753)-induced diabetic rats^[3].

Animal Model:	Rats^[1]
Dosage:	1 mg/kg
Administration:	p.o., repeated and a single dose for 5 days
Result:	The repeated administration of ipidacrine improved amnesia induced by nucleus basalis of meynert (NBM) lesions in the passive avoidance task in rats.

Animal Model:	Rats^[1]
Dosage:	3, 10, 30 mg/kg
Administration:	p.o., a single dose
Result:	Decreased pupil size and increased salivation at 3 mg/kg, decreased spontaneous movements at 10 mg/kg and decreased body temperature and induced tremor at 30 mg/kg in rats.

Animal Model:	Rats with streptozotocin (STZ) (HY-13753) induced diabetes mellitus-induced erectile dysfunction (DMED)^[1]
Dosage:	6.7 mg/kg
Administration:	crushed, suspended in 1% starch solution and administered intragastrically daily for 14 days
Result:	Ipidacrine was as effective as sildenafil and could significantly improve DMED symptoms.

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE manufacturers

Career Henan Chemical Co

Product: 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE 62732-44-9
Price: US $1000.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10KG
Release date: 2018-08-04

62732-44-9, 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINERelated Search:

ipilimumab 2,6-DIMETHYL-PYRIDIN-4-YLAMINE 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate (1:1:1) Cyclopenta[b]pyridine 5,6,7,8-tetrahydro-3-methylquinoline 5,6,7,8-Tetrahydroquinaldine 4-PYRIDINAMINE, 5-ETHYL-2-METHYL- 3,5-dimethylpyridin-4-amine AMIRIDIN 4-Pyridinamine,2,3-dimethyl-(9CI) 2,6-diethylpyridine 3,5-DIETHYL PYRIDINE 5-BUTYL-2-METHYL-PYRIDINE 4-AMINO-2-METHYL-5,6,7,8-TETRAHYDROQUINOLINE 2,6-DIPROPYL PYRIDINE 2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE 2,5-diethylpyridine

9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta(b)quinoline monohydrochloride

MFCD11052605

1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine

CBI-BB ZERO/005050

AURORA KA-7699

2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLIN-9-YLAMINE

9-AMINO-2,3,5,6,7,8-HEXAHYDRO-1H-CYCLOPENTA[B]QUINOLINE

AKOS MSC-0106

2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate

9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopentaxinolina monohydrate

2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine

Takinocrine

1H-Cyclopenta(B)quinolin-9-amine, 2,3,5,6,7,8-hexahydro-

Brn 0475930

Unii-cv71vtp0vn

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine(SALTDATA: HCl H2O)

8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylaMine

1H-Cyclopenta(b)quinoline, 2,3,5,6,7,8-hexahydro-9-amino-, monohydrochloride

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-ylamine hydrochloride

2,3,5,6,7,8-Hexahydro-9-amino-1H-cyclopenta(b)quinoline hydrochloride

Ipidacrine,inhibit,cholinesterase,nootropic,Inhibitor,Cholinesterase (ChE),Alzheimer disease

Ipidacrine, 10 mM in DMSO

62732-44-9