NEUROPEPTIDE FF

ChemicalBook > CAS DataBase List > NEUROPEPTIDE FF

Product Name: NEUROPEPTIDE FF
CAS No.: 99566-27-5
Chemical Name: NEUROPEPTIDE FF
Synonyms: NPFF;NPAF;ninamide;F-8-F-NH2;FLFQPQRF-NH2;NEUROPEPTIDE FF;Neuropeptide FF TFA;Neuropeptide FF (cattle);Neuropeptide FF F-8-F-NH2;NEUROPEPTIDE FF USP/EP/BP
CBNumber: CB3750458
Molecular Formula: C54H76N14O10
Formula Weight: 1081.27
MOL File: 99566-27-5.mol

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NEUROPEPTIDE FF Property

storage temp.: −20°C
solubility: Water: 1 mg/ml
form: Solid
color: White to off-white
Water Solubility: Soluble to 0.50 mg/ml in water.

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J66509
Product name: Neuropeptide FF
Packaging: 1mg
Price: $58.2
Updated: 2023/06/20

Cayman Chemical

Product number: 24548
Product name: Neuropeptide FF (trifluoroacetate salt)
Purity: ≥95%
Packaging: 1mg
Price: $158
Updated: 2024/03/01

Tocris

Product number: 3137
Product name: Neuropeptide FF
Packaging: 1
Price: $162
Updated: 2021/12/16

Usbiological

Product number: 027103
Product name: Neuropeptide FF
Packaging: 96Tests
Price: $864
Updated: 2021/12/16

Usbiological

Product number: 027102
Product name: Neuropeptide FF
Packaging: 96Tests
Price: $879
Updated: 2021/12/16

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NEUROPEPTIDE FF Chemical Properties,Usage,Production

Description

Neuropeptide FF (NPFF) is a peptide expressed in the brain and spinal cord that shares a precursor protein with neuropeptide AF. NPFF is expressed primarily in the posterior pituitary, hypothalamus, and medulla. It is an agonist at NPFF1 and NPFF2 receptors (K_is = 2.82 and 0.21 nM, respectively, for human recombinant receptors) that inhibits forskolin-induced cAMP production in CHO cells (EC₅₀s = 236 and 2.3 nM, respectively). NPFF activates parvocellular neurons in the paraventricular nucleus (PVN) of the hypothalamus to stimulate oxytocin release from their projections in the brain stem, thereby regulating baroreflex control of heart rate. However, it inhibits magnocellular PVN neurons by enhancing GABAergic input. It is also found in plasma and exogenous administration briefly increases mean arterial pressure (MAP) by 40 mm Hg in rats, an effect that is only partially blocked by the norepinephrine competitor guanethidine and the α₁-adrenergic receptor antagonist prazosin . NPFF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol.

Uses

Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects.

storage

Store at -20°C

NEUROPEPTIDE FF Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NEUROPEPTIDE FF manufacturers

Career Henan Chemical Co

Product: NEUROPEPTIDE FF 99566-27-5
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

99566-27-5, NEUROPEPTIDE FFRelated Search:

NEUROPEPTIDE AF (HUMAN) NEUROPEPTIDE Y (13-36), PORCINE SYNTHETI C >97% PANCREATIC POLYPEPTIDE, RAT SUBSTANCE P (2-11) SUBSTANCE P (6-11) Substance P (1-7)(TFA) substance P (3-11) (LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA Galanin (1-16), mouse, porcine, rat TFA NEUROPEPTIDE F GALANIN, PORCINE GLY-LEU-MET-NH2 H-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2 H-LEU-PRO-GLY-LEU-PRO-SER-ALA-ALA-SER-SER-GLU-ASP-ALA-GLY-GLN-SER-NH2 SUBSTANCE P (1-9) SUBSTANCE P NEUROPEPTIDE Y (HUMAN, RAT)

PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE AMIDE

PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2

NPFF

NEUROPEPTIDE FF

H-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2

F-8-F-NH2

ninamide

phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylala

POTASSIUM FERROCYANIDE TRIHYDRATE*ACS RE AGENT

Neuropeptide FF F-8-F-NH2

phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide

Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2

Neuropeptide FF F-8-F-NH2, NPFF, F-8-F-aMide

F-8-F-NH2, NPFF, F-8-F-aMide

ANTI-NPFF (C-TERM) antibody produced in rabbit

FMRFamide-related peptides

NPAF

Neuropeptide FF (trifluoroacetate salt)

L-Phenylalaninamide, L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl-

Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide >=95% (HPLC)

NEUROPEPTIDE FF USP/EP/BP

Neuropeptide FF (cattle)

FLFQPQRF-NH2

Neuropeptide FF trifluoroacetate salt (NPFF)

Neuropeptide FF TFA

Rabbit Anti-NPFF antibody

99566-27-5

C54H76N14O10

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