1H-1,2,4-Triazole-3,5-diamine

Product Name: 1H-1,2,4-Triazole-3,5-diamine
CAS No.: 1455-77-2
Chemical Name: 1H-1,2,4-Triazole-3,5-diamine
Synonyms: 3,5-DIAMINO-1,2,4-TRIAZOLE;GUANAZOLE;4H-1,2,4-TRIAZOLE-3,5-DIAMINE;nsc1895;MC 51762;NSC 1895;NCI-C04819;TIMTEC-BB SBB004371;Guanazole (VAN) (8CI);3,5-diamino-s-triazol
CBNumber: CB3756001
Molecular Formula: C2H5N5
Formula Weight: 99.09
MOL File: 1455-77-2.mol

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1H-1,2,4-Triazole-3,5-diamine Property

Melting point:: 202-205 °C (lit.)
Boiling point:: 473.7±28.0 °C(Predicted)
Density: 1.686±0.06 g/cm3(Predicted)
refractive index: 1.7330 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: H₂O: clear to hazy
form: powder
pka: 12.10±0.40(Predicted)
color: white
Water Solubility: Soluble in water.
BRN: 112467
Stability:: Stability Air sensitive. Reacts with acids and oxidizing agents.
InChIKey: PKWIYNIDEDLDCJ-UHFFFAOYSA-N
CAS DataBase Reference: 1455-77-2(CAS DataBase Reference)
NIST Chemistry Reference: 3,5-Diamino-1,2,4-triazole(1455-77-2)
EPA Substance Registry System: Guanazole (1455-77-2)

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Safety

Hazard Codes: Xn,Xi,C
Risk Statements: 22-34
Safety Statements: 36/37-45-36/37/39-27-26
WGK Germany: 3
RTECS: XZ4535000
TSCA: Yes
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D26202
Product name: 3,5-Diamino-1,2,4-triazole
Purity: 98%
Packaging: 25g
Price: $189
Updated: 2024/03/01

Sigma-Aldrich

Product number: D26202
Product name: 3,5-Diamino-1,2,4-triazole
Purity: 98%
Packaging: 100g
Price: $683
Updated: 2024/03/01

TCI Chemical

Product number: D2587
Product name: 3,5-Diamino-1,2,4-triazole
Purity: >97.0%(T)
Packaging: 5g
Price: $32
Updated: 2024/03/01

TCI Chemical

Product number: D2587
Product name: 3,5-Diamino-1,2,4-triazole
Purity: >97.0%(T)
Packaging: 25g
Price: $128
Updated: 2024/03/01

Alfa Aesar

Product number: B22775
Product name: 3,5-Diamino-1,2,4-triazole, 98+%
Packaging: 5g
Price: $33.65
Updated: 2024/03/01

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1H-1,2,4-Triazole-3,5-diamine Chemical Properties,Usage,Production

Chemical Properties

colourless crystals or faintly yellow powder

Uses

3,5-Diamino-1,2,4-triazole is used as an inhibitor of DNA synthesis. It also serves as an antitumor agents in the treatment of epigenetically-based diseases. It acts as a corrosion inhibitor for copper.

Definition

ChEBI: An aromatic amine that is 1,2,4-triazole substituted at positions 3 and 5 by amino groups.

General Description

Colorless crystals.

Air & Water Reactions

1H-1,2,4-Triazole-3,5-diamine is sensitive to air. Dust can be explosive when suspended in air at specific concentrations. Water soluble.

Reactivity Profile

The triazoles, of which 1H-1,2,4-Triazole-3,5-diamine is a member, are a group of highly explosive materials that are sensitive to heat, friction, and impact. Sensitivity varies with the type of substitution to the triazole ring. The amine substituted derivatives, 1H-1,2,4-Triazole-3,5-diamine, tend not to be explosion sensitive. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. 1H-1,2,4-Triazole-3,5-diamine forms salts readily with acids.

Health Hazard

SYMPTOMS: 1H-1,2,4-Triazole-3,5-diamine is stable under normal laboratory conditions.

Fire Hazard

Flash point data for 1H-1,2,4-Triazole-3,5-diamine are not available. 1H-1,2,4-Triazole-3,5-diamine is probably combustible.

Safety Profile

Human systemic effects by intravenous route: leukopenia (reduced white blood cell count) and thrombo cytopenia (reduced blood platelet count). Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

The triazole crystallises from water or EtOH. [Beilstein 26 III/IV 1161.]

1H-1,2,4-Triazole-3,5-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-1,2,4-Triazole-3,5-diamine Suppliers

Americas 1 Australia 1 Austria 1 Belgium 2 Canada 1 China 233 Europe 2 Germany 10 India 10 Italy 1 Japan 4 Russia 2 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 9 United States 43 Global 326

Hubei Youyicheng Industrial Co., Ltd.

Tel: 19521119694
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Email: 1572909019@qq.com
Country: China
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Hefei Hirisun Pharmatech Co., Ltd.

Tel: +86-0551-62678551 +86-15056975894
Fax: 0551-62678551
Email: sales@hirisunpharm.com
Country: China
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Wuhan Hongde Yuexin Pharmatech Co.,Ltd

Tel: 027-83855396 15271852016
Fax: 027-83855396
Email: whhdyxchem@sina.com
Country: China
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Henan Evonik Biotechnology Co. LTD

Tel: 16650615803
Email: hnyingchuang@163.com
Country: China
ProdList: 3970
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Wuhan EnTai Technology Development Co,.Ltd

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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3576
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

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View Lastest Price from 1H-1,2,4-Triazole-3,5-diamine manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 1H-1,2,4-Triazole-3,5-diamine 1455-77-2
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-19

Hebei Mojin Biotechnology Co., Ltd

Product: 1H-1,2,4-Triazole-3,5-diamine 1455-77-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-11

Hebei Guanlang Biotechnology Co., Ltd.

Product: 1H-1,2,4-Triazole-3,5-diamine 1455-77-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-04-06

1455-77-2, 1H-1,2,4-Triazole-3,5-diamineRelated Search:

1H-1,2,4-Triazole-3,5-diamine 3,5-DIAMINO-1,2,4-TRIAZOLE,3,5-diamino-1,3,5-triazole,3 5-DIAMINO-1 2 4-TRIAZOLE 98% 1,2,4-Triazole 3,5,7-TRIAMINO-1,2,4-TRIAZOLO[4,3-A]-1,3,5-TRIAZINE N3-(4-CHLOROPHENYL)-1H-1,2,4-TRIAZOLE-3,5-DIAMINE N3,N3,N5,N5-TETRAMETHYL-1-([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 1-phenyl-1H-1,2,4-triazole-3,5-diamine 1-(4-FLUOROBENZYL)-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 1-(2,6-DICHLOROBENZYL)-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 1H-1,2,4-Triazole-3,5-diamine,N-propyl-(9CI) N-phenyl-1H-1,2,4-triazole-3,5-diamine 1-[(4-METHOXYPHENYL)SULFONYL]-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE N3,N3,N5,N5-TETRAMETHYL-1-(4-METHYLBENZYL)-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 4H-1,2,4-Triazole-3,4-diamine,5-ethyl-N-methyl-N-(phenylmethylene)-(9CI) 5-METHYL-1,2,4-TRIAZOLE-3,4-DIAMINE 4H-1,2,4-Triazole-3,4-diamine 1-(4-BROMOBENZYL)-N3,N3,N5,N5-TETRAMETHYL-1H-1,2,4-TRIAZOLE-3,5-DIAMINE 7-(4-BROMOPHENYL)-2-MORPHOLINO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE

3,5-DiaMino-1,2,4-triazole, 98% 25GR

3,5-Diamino-1H-1,2,4-triazole, Guanazole

1,2,4-triazolidine-3,5-diiMine

Guanazole SynonyMs 1H-1,2,4-Triazole-3,5-diaMine

(5-amino-2H-1,2,4-triazol-3-yl)amine

Guanazole (VAN) (8CI)

4H-1,2,4-TRIAZOLE-3,5-DIAMINE

3-AMINO-1H-1,2,4-TRIAZOL-5-YLAMINE

3,5-DIAMINO-1,2,4-TRIAZOLE

3,5-DIAMINO-1H-1,2,4-TRIAZOLE

1,2,4-Triazolidine, 3,5-diimino-

3,5-diamino-s-triazol

3,5-Diamino-s-triazole

MC 51762

NCI-C04819

NSC 1895

nsc1895

s-Triazole, 3,5-diamino-

GUANAZOLE

TIMTEC-BB SBB004371

1H-1,2,4-TRIAZOLE-3,5-DIAMINE

3,5-Diamino-1,2,4-triazole (Guanazole)

1H-1,2,4-Triazole-3,5-diamine (Guanazole)

GUANETIDINEHEMISULPHATE

3,5-DIAMINO-1,2,4-TRIAZOLE, 98+%

2,3-Diamino-1H-1,2,4-triazole

Guanazole 3,5-Diamino-1,2,4-triazole (Guanazole) 3,5-Diamino-1H-1,2,4-triazole 1H-1,2,4-triazole-3,5-diamine

3,5-Diamino-1,2,4-triazole, 98%, for synthesis

3,5-Diamino-1,2,4-triazole&gt

1455-77-2

1455-72-2

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