ChemicalBook > CAS DataBase List > (SAR9,MET(O2)11)-SUBSTANCE P

(SAR9,MET(O2)11)-SUBSTANCE P

Product Name
(SAR9,MET(O2)11)-SUBSTANCE P
CAS No.
110880-55-2
Chemical Name
(SAR9,MET(O2)11)-SUBSTANCE P
Synonyms
Bhsar-sp;[Sar9, Met(O2)11;[Sar9]SP sulfone;RPKPQQFFSARLM(O2);[Sar9]SP sulphone;[Sar9,Met(O2)11]SP;9-Sar-substance p sulfone;[Sar9]substance P sulphone;(SAR9,MET(O2)11)-SUBSTANCE P;9-Sar-11-Met(o2)-substance p
CBNumber
CB3758823
Molecular Formula
C64H100N18O15S
Formula Weight
1393.66
MOL File
110880-55-2.mol
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(SAR9,MET(O2)11)-SUBSTANCE P Property

Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O : 50 mg/mL (35.88 mM; Need ultrasonic)
form 
Lyophilized solid.
pka
13.31±0.20(Predicted)
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O2)-NH2
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S3672
Product name
[Sar9, Met(O2)11]-Substance P
Purity
≥95% (HPLC)
Packaging
1mg
Price
$185
Updated
2024/03/01
Sigma-Aldrich
Product number
S3672
Product name
[Sar9, Met(O2)11]-Substance P
Purity
≥95% (HPLC)
Packaging
5mg
Price
$837
Updated
2023/01/07
Tocris
Product number
1178
Product name
[Sar9, Met(O2)11]-Substance P
Packaging
1
Price
$171
Updated
2021/12/16
TRC
Product number
S142513
Product name
[Sar9, Met(O2)11]-Substance P
Packaging
2.5mg
Price
$210
Updated
2021/12/16
ChemScene
Product number
CS-7605
Product name
[Sar9, Met(O2)11]-Substance P
Purity
98.45%
Packaging
5mg
Price
$348
Updated
2021/12/16
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(SAR9,MET(O2)11)-SUBSTANCE P Chemical Properties,Usage,Production

Uses

[Sar9,Met(O2)11]-Substance P is a potent and selective NK1 tachykinin receptor agonist (1). The NK1 tachykinin receptor is a member of the G-protein coupled receptor family and can be found in neurons, brainstem, and vascular endothelial cells (2,3). NK1 tachykinin receptor is a therapeutic target for pancreatic cancer (4).

Biochem/physiol Actions

Highly selective NK-1 receptor agonist.

storage

Store at -20°C

(SAR9,MET(O2)11)-SUBSTANCE P Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (SAR9,MET(O2)11)-SUBSTANCE P manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(SAR9,MET(O2)11)-SUBSTANCE P 110880-55-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

110880-55-2, (SAR9,MET(O2)11)-SUBSTANCE PRelated Search:


  • (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfonyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide
  • [Sar9,Met(O2)11]-Substance P,Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2?, >98%
  • [SAR9,MET(O2)11]-SUBSTANCE P?, >98%
  • H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2
  • ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2
  • (SAR9,MET(O2)11)-SUBSTANCE P
  • RPKPQQFFSARLM(O2)
  • [SAR9 ,MET(O2 )11 ]-SUBSTANCE P HIGHLY SPECIFIC NEUROKININ NK1 RECEPTOR 97+%
  • [Sar9,met(o2)11]-substancephighlyspecificneurokininnk1receptor
  • substance P, Sar(9)-Met(O2)(11)-
  • [Sar9, Met(O2)11
  • 9-Sar-11-Met(o2)-substance p
  • 9-Sarcosyl-11-methionine(o2)-substance p
  • 9-Sar-substance p sulfone
  • Bhsar-sp
  • Bolton hunter-9-sar-11-Met(02)-substance p
  • Bolton-hunter reagent-substance p. sar(9)-Met(02)(11)
  • Sarcosyl(9)-substance p sulfone
  • [Sar9,Met(O2)11]SP
  • [Sar9]SP sulfone
  • [Sar9]SP sulphone
  • [Sar9]substance P sulphone
  • L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Sar-L-Leu-4-(Methylsulfonyl)-L-Abu-NH2
  • Substance P, 9-(N-methylglycine)-, S,S-dioxide
  • (SAR9,MET(O2)11)-SUBSTANCE P USP/EP/BP
  • Inhibitor,Tachykinin receptor,[Sar9,Met(O2)11]-Substance P,NK receptor,Neurokinin Receptor,[Sar9,Met(O2)11] Substance P,[Sar9,Met(O2)11]Substance P,inhibit,[Sar-9,Met(O2)11]-Substance P
  • Substance p,9-(N-methylglycine)-11-(s,s-dioxido-L-methioninamide)-
  • (Sar?,Met(O?)??)-Substance P
  • 110880-55-2
  • C64H100N18O15S
  • C64H97N19O15S
  • BioChemical
  • Amino Acids and Peptides
  • Agonist
  • Biochemicals and Reagents
  • Peptides
  • Tachykinins
  • Tachykinin receptor