9-IODOPHENANTHRENE

9-IODOPHENANTHRENE Property

Melting point:

91-93 °C (lit.)

Boiling point:

411.0±14.0 °C(Predicted)

Density 

1.692±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

Appearance

Light yellow to yellow Solid

Stability:

Stable, but light sensitive - store in the dark. Incompatible with strong oxidizing agents.

InChI

InChI=1S/C14H9I/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9H

InChIKey

CBFIPOTVFMLMFQ-UHFFFAOYSA-N

SMILES

C1=C2C(C3C(C(I)=C2)=CC=CC=3)=CC=C1

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

9-IODOPHENANTHRENE Chemical Properties,Usage,Production

Chemical Properties

solid

Synthesis

General procedure for the synthesis of 9-iodophenanthrene from 9-bromophenanthrene: General method: aryl bromide (10 mmol) was dissolved in anhydrous THF (30 mL) and cooled to -78 °C at room temperature. Slowly add n-butyllithium (1.6 M, dissolved in hexane; 7.5 mL; 12 mmol) dropwise. After 15 min of reaction, a solution of anhydrous THF (10 mL) with iodine (I2, 3.81 g; 15 mmol) was added, followed by gradual warming of the reaction mixture to room temperature and stirring overnight. After completion of the reaction, the mixture was concentrated under vacuum. Water (H2O) was added to the residue and extracted with dichloromethane (DCM, 3 times). The organic phases were combined and washed sequentially with saturated sodium thiosulfate (Na2S2O5) solution and water. The organic phase was dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure, and the resulting crude product was purified by column chromatography.

References

[1] Synlett, 2013, vol. 24, # 20, p. 2730 - 2734
[2] Synthesis, 1986, # 1, p. 121 - 122
[3] Journal of Organic Chemistry, 2009, vol. 74, # 12, p. 4650 - 4653
[4] Tetrahedron Letters, 1999, vol. 40, # 36, p. 6671 - 6672
[5] Beilstein Journal of Organic Chemistry, 2011, vol. 7, p. 1499 - 1503