EQUILENIN
- Product Name
- EQUILENIN
- CAS No.
- 517-09-9
- Chemical Name
- EQUILENIN
- Synonyms
- E 400;NSC 9901;EQUILENIN;Equilenina;Equilenine;D-EQUILENIN;l-Equilenin;Isoequilenin;(+)-EQUILENIN;Isoequilenine
- CBNumber
- CB3774265
- Molecular Formula
- C18H18O2
- Formula Weight
- 266.33
- MOL File
- 517-09-9.mol
EQUILENIN Property
- Melting point:
- 258-259°
- alpha
- D16 +87° (12.8 mg made up to 1.8 ml in dioxane)
- Boiling point:
- 349.54°C (rough estimate)
- Density
- 1.1305 (rough estimate)
- refractive index
- 1.4800 (estimate)
- Flash point:
- 2 °C
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- pKa 9.72 (H2O t=25.0±0.02 ) (Uncertain);9.75±0.06 (Uncertain)
- form
- Solid
- color
- Pale Yellow to Light Beige
- Water Solubility
- 1.52mg/L(25 ºC)
- EPA Substance Registry System
- Equilenin (517-09-9)
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22-36-48-40
- Safety Statements
- 16-26-36-36/37
- RIDADR
- UN 1648 3/PG 2
- WGK Germany
- 2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 33693
- Product name
- Equilenin solution
- Purity
- 100?μg/mL in acetonitrile, VETRANAL?, analytical standard
- Packaging
- 2ml
- Price
- $73.1
- Updated
- 2022/05/15
- Product number
- 23322
- Product name
- Equilenin
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 23322
- Product name
- Equilenin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $183
- Updated
- 2024/03/01
- Product number
- E592400
- Product name
- Equilenin
- Packaging
- 2mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- FE22774
- Product name
- Equilenin
- Packaging
- 2mg
- Price
- $400
- Updated
- 2021/12/16
EQUILENIN Chemical Properties,Usage,Production
Uses
Equilenin is a naturally occuring estrogenic steroidal hormone (1,2) isolated from urine of pregnant mares (3). Not found in human urine. Component of conjugated estrogenic hormones. Estrogen. This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Uses
Estrogenic steroidal hormone isolated from urine of pregnant mares. Occurs naturally in the d-form. Not found in human urine. Component of conjugated estrogenic hormones. Estrogen.
Definition
ChEBI: Equilenin is a 3-hydroxy steroid that is estrone which carries two double bonds at positions 6 and 8. It is found in the urine of pregnant mare's and extensively used for estrogen replacement therapy in postmenopausal women. It has a role as a mammalian metabolite and an antioxidant. It is a 3-hydroxy steroid and a 17-oxo steroid.
Purification Methods
Crystallise (+)-equilenin from EtOH (solubility is 0.63% at 18o, 2.5% at 78o), aqueous EtOH or *C6H6 (Norite) and dry it in a vacuum. It sublimes on melting and at 170-180o/0.01mm. The acetate crystallises from MeOH with m 165-167o and [ ] D +71o (c 1, CHCl3). [Bachmann et al. J Am Chem Soc 62 824 1940, Beilstein 8 III 1522, 1523, 1525, 8 IV 1420.]