VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- Product Name
- VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- CAS No.
- 106021-96-9
- Chemical Name
- VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- Synonyms
- Sclavo peptide;IL-1B (163-171) (HUMAN);interleukin-1beta(163-171;IL-1BETA (163-171) (HUMAN);INTERLEUKIN-1B (163-171) (HUMAN);b-Interleukin I (163-171), human;β-Interleukin I (163-171), human;Interleukin-1β (163-171) (human);β-Interleukin I (163-171), human;VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- CBNumber
- CB3776638
- Molecular Formula
- C39H64N12O19
- Formula Weight
- 1004.99
- MOL File
- 106021-96-9.mol
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Property
- Boiling point:
- 1682.6±65.0 °C(Predicted)
- Density
- 1.419±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- insoluble in EtOH; ≥100.4 mg/mL in DMSO; ≥24.75 mg/mL in H2O
- form
- solid
- pka
- 3.14±0.10(Predicted)
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- A1026
- Product name
- β-InterleukinI(163-171),human
- Packaging
- 5mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- A1026
- Product name
- β-InterleukinI(163-171),human
- Packaging
- 10mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- A1026
- Product name
- β-InterleukinI(163-171),human
- Packaging
- 25mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- PEP0009164
- Product name
- BETA-INTERLEUKIN I(163-171)-HUMAN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $612.15
- Updated
- 2021/12/16
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Chemical Properties,Usage,Production
Biological Activity
β-interleukin i (163-171), human(c39h64n12o19), a peptide with the sequence val-gln-gly-glu-glu-ser-asn-asp-lys, mw= 1005. interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). interleukin 1 alpha and interleukin 1 beta (il-1 alpha and il-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.interleukin-1 beta (il-1β) also known as catabolin, is a cytokine protein that in humans is encoded by the il1b gene. il-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). cytosolic thiol protease cleaves the product to form mature il-1β. il-1β is a member of the interleukin 1 cytokine family. this cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.figure1 formula of b-interleukin i (163-171), humanfigure2 structure of b-interleukin i
Biochem/physiol Actions
IL1B (interleukin 1 β) is an immune-activating cytokine. In presence of infection or cell stress, it gets converted into active mature form.
References
1. Contassot E, Beer HD, French LE (2012). "Interleukin-1, inflammasomes, autoinflammation and the skin". Swiss Med Wkly 142: w135902. Matzinger P (2012). "The evolution of the danget theory. Interview by Lauren Constable, Commissioning Editor". Expert Rev Clin Immunol 8 (4): 311-7.3. Sahoo M, Ceballos-Olvera I, del Barrio L, Re F (2011). "Role of the inflammasome, IL-1β, and IL-18 inbacterial infections". ScientificWorldJournal 11: 2037-50.
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Preparation Products And Raw materials
Raw materials
Preparation Products
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