ChemicalBook > CAS DataBase List > VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS

VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS

Product Name
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
CAS No.
106021-96-9
Chemical Name
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
Synonyms
Sclavo peptide;IL-1B (163-171) (HUMAN);interleukin-1beta(163-171;IL-1BETA (163-171) (HUMAN);INTERLEUKIN-1B (163-171) (HUMAN);b-Interleukin I (163-171), human;β-Interleukin I (163-171), human;Interleukin-1β (163-171) (human);β-Interleukin I (163-171), human;VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
CBNumber
CB3776638
Molecular Formula
C39H64N12O19
Formula Weight
1004.99
MOL File
106021-96-9.mol
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VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Property

Boiling point:
1682.6±65.0 °C(Predicted)
Density 
1.419±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
insoluble in EtOH; ≥100.4 mg/mL in DMSO; ≥24.75 mg/mL in H2O
form 
solid
pka
3.14±0.10(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A1026
Product name
β-InterleukinI(163-171),human
Packaging
5mg
Price
$60
Updated
2021/12/16
ApexBio Technology
Product number
A1026
Product name
β-InterleukinI(163-171),human
Packaging
10mg
Price
$100
Updated
2021/12/16
ApexBio Technology
Product number
A1026
Product name
β-InterleukinI(163-171),human
Packaging
25mg
Price
$140
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0009164
Product name
BETA-INTERLEUKIN I(163-171)-HUMAN
Purity
95.00%
Packaging
1MG
Price
$612.15
Updated
2021/12/16
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VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Chemical Properties,Usage,Production

Biological Activity

β-interleukin i (163-171), human(c39h64n12o19), a peptide with the sequence val-gln-gly-glu-glu-ser-asn-asp-lys, mw= 1005. interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). interleukin 1 alpha and interleukin 1 beta (il-1 alpha and il-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.interleukin-1 beta (il-1β) also known as catabolin, is a cytokine protein that in humans is encoded by the il1b gene. il-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). cytosolic thiol protease cleaves the product to form mature il-1β. il-1β is a member of the interleukin 1 cytokine family. this cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.figure1 formula of b-interleukin i (163-171), humanfigure2 structure of b-interleukin i

Biochem/physiol Actions

IL1B (interleukin 1 β) is an immune-activating cytokine. In presence of infection or cell stress, it gets converted into active mature form.

References

1. Contassot E, Beer HD, French LE (2012). "Interleukin-1, inflammasomes, autoinflammation and the skin". Swiss Med Wkly 142: w135902. Matzinger P (2012). "The evolution of the danget theory. Interview by Lauren Constable, Commissioning Editor". Expert Rev Clin Immunol 8 (4): 311-7.3. Sahoo M, Ceballos-Olvera I, del Barrio L, Re F (2011). "Role of the inflammasome, IL-1β, and IL-18 inbacterial infections". ScientificWorldJournal 11: 2037-50.

VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Preparation Products And Raw materials

Raw materials

Preparation Products

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106021-96-9, VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYSRelated Search:


  • IL-1BETA (163-171) (HUMAN)
  • IL-1B (163-171) (HUMAN)
  • H-VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS-OH
  • INTERLEUKIN-1BETA FRAGMENT 163-171 HUMAN
  • INTERLEUKIN-1BETA (163-171) (HUMAN)
  • INTERLEUKIN-1B (163-171) (HUMAN)
  • BETA-INTERLEUKIN I (163-171), HUMAN
  • VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
  • interleukin-1beta(163-171
  • interleukin-1B fragment 163-171 human
  • interleukin-1β fragment 163-171 human
  • b-Interleukin I (163-171), human
  • β-Interleukin I (163-171), human
  • IL-1β (163-171) (human)|β-Interleukin I (163-171),human
  • L-Lysine, L-valyl-L-glutaminylglycyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-asparaginyl-L-α-aspartyl-
  • Sclavo peptide
  • IL-1β (163-171) (human)|β-Interleukin I (163-171),human
  • Interleukin-1β (163-171) (human)
  • β-Interleukin I (163-171), human
  • Interleukin-1β Fragment 163-171 human
  • 106021-96-9
  • C39H64N12O19
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Interleukins (IL)
  • IL-1 and Receptors
  • Cytokines, Growth Factors and Hormones
  • Cytokines and Growth Factors
  • Cytokine/Growth FactorStem Cell Differentiation
  • CytokinesCytokines and Growth Factors
  • CytokinesStem Cell Expansion
  • IL-1 and ReceptorsObesity Research
  • Interleukin-1 (IL-1)
  • Cytokines Growth Factors and Hormones (Obesity)
  • Cytokines/Growth Factors/Chemokines
  • Hematopoietic Stem Cell Biology
  • Hematopoietic Stem Cell Expansion/Differentiation
  • Immunology
  • peptides
  • Interleukins (IL)