ChemicalBook > CAS DataBase List > Azaconazole

Azaconazole

Product Name
Azaconazole
CAS No.
60207-31-0
Chemical Name
Azaconazole
Synonyms
RODEWOD;madurox;R-28644;Aids108350;azoconozole;SAFETRAY SL;AZACONAZOLE;AZOCONAZOLE;Aids-108350;Azaconazol, Vetranal
CBNumber
CB3780871
Molecular Formula
C12H11Cl2N3O2
Formula Weight
300.14
MOL File
60207-31-0.mol
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Azaconazole Property

Melting point:
109.9°
Boiling point:
460.7±55.0 °C(Predicted)
Density 
1.51±0.1 g/cm3(Predicted)
vapor pressure 
8.6 x l0-6 Pa (20 °C)
storage temp. 
0-6°C
pka
2.94±0.12(Predicted)
Water Solubility 
300 mg l-1 (20 °C)
CAS DataBase Reference
60207-31-0(CAS DataBase Reference)
EPA Substance Registry System
Azaconazole (60207-31-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
46
WGK Germany 
1
RTECS 
XZ4605000
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
34045
Product name
Azaconazole
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$67.6
Updated
2024/03/01
TRC
Product number
A796033
Product name
Azaconazole
Packaging
250mg
Price
$250
Updated
2021/12/16
AK Scientific
Product number
L993
Product name
Azaconazole
Packaging
100mg
Price
$126
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0122754
Product name
1-[2-(2,4-DICHLOROPHENYL)-1,3-DIOXOLAN-2-YLMETHYL]-1H-1,2,4-TRIAZOLE
Purity
95.00%
Packaging
5MG
Price
$503.83
Updated
2021/12/16
Alichem
Product number
60207310
Product name
1-((2-(2,4-Dichlorophenyl)-1,3-dioxolan-2-yl)methyl)-1H-1,2,4-triazole
Packaging
1g
Price
$659.4
Updated
2021/12/16
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Azaconazole Chemical Properties,Usage,Production

Originator

Azaconazole,Chemical

Uses

Fungicide for cultivation on wood; preservative for composite wood products.

Uses

Azaconazole is particularly active against wood-destroying and sapstain fungi. It is also used as a disinfectant in mushroom cultivation and on storage boxes for fruit and vegetables.

Definition

ChEBI: A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2,4-dichlorophenyl and 1,2,4-triazol-1-ylmethyl groups. A fungicide used mainly in ornamental crops to control canker and other diseases. Azaconazole is moderately toxic to mammals but is not expected to bioaccumulate. It is moderately toxic to birds, fish and aquatic invertebrates.

Manufacturing Process

A stirred and cooled (0°C) solution of 1-(2,4-diaminophenyl)-1-ethanone in a concentrated hydrochloric acid solution, water and acetic acid was diazotated with a solution of sodium nitrite in water. After stirring at 0°C, the whole was poured onto a solution of copper (I) chloride in a concentrated hydrochloric acid solution while stirring. The mixture was heated at 60°C. After cooling to room temperature, the product was extracted twice with 2,2'-oxybispropane. The combined extracts were washed successively with water, a diluted sodium hydroxide solution and again twice with water, dried, filtered and evaporated, yielding 1-(2,4-dichlorophenyl)-1-ethanone.
1-(2,4-Dichlorophenyl)-1-ethanon were dissolved in 1,2-ethanediol at heating. While stirring bromine were added dropwise, without external heating. After stirring at room temperature, 4-methylbenzenesulfonic acid and benzene were added. The whole was stirred and refluxed overnight with water-separator. The reaction mixture was evaporated and the residue was taken up in 2,2'- oxybispropane. The resulting solution was washed successively once with a dilute sodium hydroxide solution and 3 times with water, dried, filtered and evaporated. The residue was distilled, yielding 2-(bromomethyl)-2-(2,4- dichlorophenyl)-1,3-dioxolane.
6.9 parts of 1H-1,2,4-triazole in 150 parts of dimethylformamide were added to a stirred solution of 2.3 parts of sodium in 120 parts of methanol. The methanol was removed at normal pressure until the internal temperature of 130°C was reached. Then, 25 parts of 2-(bromomethyl)-2-(2,4- dichlorophenyl)-1,3-dioxolane were added. The reaction-mixture was stirred and refluxed for 3 h. It was allowed to cool to room temperature and poured onto water. The precipitated product was filtered off, yielding 12 parts of 1-[2- (2,4-dichlorophenyl)-1,3-dioxolan-2-yl-methyl]-1H-1,2,4-triazole, melting point 109.9°C (crystallized from diisopropylether, activated charcoal).

Therapeutic Function

Antifungal

Metabolic pathway

Little published dormation is available on the metabolism of azaconazole.

Degradation

Azaconazole is stable to light under normal storage conditions (but not in ketonic solvents). It is stable at temperatures up to 220 °C.

Azaconazole Preparation Products And Raw materials

Raw materials

Preparation Products

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Azaconazole Suppliers

Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
TianJin Alta Scientific Co., Ltd.
Tel
022-65378550-8551
Fax
+86-022-2532-9655
Email
contact@altascientific.com
Country
China
ProdList
2773
Advantage
58
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
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View Lastest Price from Azaconazole manufacturers

Career Henan Chemical Co
Product
Azaconazole 60207-31-0
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,50kg
Release date
2020-01-18

60207-31-0, AzaconazoleRelated Search:


  • AZOCONAZOLE
  • 1-[[2-(2,4-Dichlorophenyl)-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole
  • SAFETRAY SL
  • RODEWOD
  • 4-triazole,1-((2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl)methyl)-1h-2
  • azoconozole
  • madurox
  • AZACONAZOLE
  • 1-[2-(2,4-DICHLOROPHENYL)-1,3-DIOXOLAN-2-YLMETHYL]-1H-1,2,4-TRIAZOLE
  • Azaconazol, Vetranal
  • 1H-1,2,4-Triazole, 1-2-(2,4-dichlorophenyl)-1,3-dioxolan-2-ylmethyl-
  • azaconazole (bsi,iso)
  • azaconazole (ISO) 1-{[2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl]methyl}-1H-1,2.4-triazole
  • R-28644
  • Aids108350
  • Aids-108350
  • Azaconazole Solution
  • Azaconazole 10.0 μg/ml Ethyl acetate
  • Azaconazole 100 μg/ml Acetonitrile
  • C10339000 Azaconazole
  • L10339000ALAzaconazolE10μg/mLin Acetonitril
  • L10339000CY AzaconazolE10μg/mLin Cyclohexane
  • Azaconazole in Acetonitrile
  • 60207-31-0
  • C12H11Cl2N3O2