ChemicalBook > CAS DataBase List > (R)-(+)-Propylene carbonate
(R)-(+)-Propylene carbonate
- Product Name
- (R)-(+)-Propylene carbonate
- CAS No.
- 16606-55-6
- Chemical Name
- (R)-(+)-Propylene carbonate
- Synonyms
- R-Prpylene Carbonate;(R)-PROPYLENE CARBONATE;(R)-Propandiolcarbonate;(R)-PropyleneCarbonate>(R)-(+)-PROPYLENE CARBONATE;(R)-1,2-PROPYLENE CARBONATE;(R)-1,2-PROPANEDIOL CARBONATE;Tenofovirdisoproxil Impurity 38;(R)-Propylene Carbonate,99%e.e.;(R)-(+)-1,2-PROPYLENE CARBONATE
- CBNumber
- CB3783423
- Molecular Formula
- C4H6O3
- Formula Weight
- 102.09
- MOL File
- 16606-55-6.mol
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(R)-(+)-Propylene carbonate Property
- Boiling point:
- 240 °C(lit.)
- Density
- 1.189 g/mL at 25 °C(lit.)
- vapor pressure
- 0.59 psi ( 20 °C)
- refractive index
- n20/D 1.422(lit.)
- Flash point:
- >230 °F
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Sparingly)
- form
- Oil
- color
- Clear Colourless to Pale Yellow
- Specific Gravity
- 1.189
- optical activity
- [α]20/D +2°, neat
- Water Solubility
- 175 g/L (25 ºC)
- InChI
- InChI=1S/C4H6O3/c1-3-2-6-4(5)7-3/h3H,2H2,1H3/t3-/m1/s1
- InChIKey
- RUOJZAUFBMNUDX-GSVOUGTGSA-N
- SMILES
- O1C[C@@H](C)OC1=O
- CAS DataBase Reference
- 16606-55-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 540013
- Product name
- (R)-(+)-Propylene carbonate
- Purity
- 98%
- Packaging
- 5g
- Price
- $70.1
- Updated
- 2025/07/31
TCI Chemical
- Product number
- P1485
- Product name
- (R)-Propylene Carbonate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $49
- Updated
- 2025/07/31
TCI Chemical
- Product number
- P1485
- Product name
- (R)-Propylene Carbonate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $241
- Updated
- 2025/07/31
TRC
- Product number
- P836750
- Product name
- (R)-1,2-PropyleneCarbonate
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 119892
- Product name
- (R)-4-Methyl-1,3-dioxolan-2-one
- Purity
- 95+%
- Packaging
- 10g
- Price
- $54
- Updated
- 2021/12/16
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(R)-(+)-Propylene carbonate Chemical Properties,Usage,Production
Description
(R)-(+)-Propylene carbonate, also known as (R)-1,2-Propanediol cyclic carbonate, presents as a colorless to pale yellow liquid. This compound should keep the container tightly closed and stored in a cool and dark place. For best results, store under inert gas, protected from moisture, as this substance is moisture-sensitive. (R)-(+)-Propylene carbonate is incompatible with oxidizing agents and acids. This chemical causes skin irritation as well as serious eye irritation.
Chemical Properties
Colorless to light yellow liqui
Uses
(R)-1,2-Propylene Carbonate (cas# 16606-55-6) is a compound useful in organic synthesis.
Synthesis
4254-14-2
105-58-8
16606-55-6
The general procedure for the synthesis of R-propylene carbonate from (R)-1,2-propanediol and diethyl carbonate was as follows: (R)-1,2-propanediol (38.05 kg, 500 mol) was added to a glass-lined reactor, followed by the addition of diethyl carbonate (70.88 kg, 600 mol) and sodium ethoxide (3.4 kg, 50 mol). The reaction mixture was heated to 105-110 °C and maintained for 8 hours. After completion of the reaction, unreacted diethyl carbonate was removed by distillation under reduced pressure. After the reaction mixture was cooled to room temperature, the insoluble material was removed by filtration. Finally, the solvent was removed by evaporation of the filtrate to afford R-propylene carbonate (34.24 kg, purity ≥99%) in 90% yield.
References
[1] Patent: CN105859781, 2016, A. Location in patent: Paragraph 0011-0012
[2] Patent: US2010/216822, 2010, A1. Location in patent: Page/Page column 13
[3] Tetrahedron Letters, 1998, vol. 39, # 14, p. 1853 - 1856
[4] Patent: EP1243590, 2002, A2. Location in patent: Page 9
[5] Patent: CN102977146, 2016, B. Location in patent: Paragraph 0016; 0021; 0023
(R)-(+)-Propylene carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-(+)-Propylene carbonate manufacturers
Shenzhen Nexcon Pharmatechs Ltd.
- Product
- (R)-(+)-Propylene carbonate 16606-55-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20000
- Release date
- 2025-07-29
Shaanxi Dideu New Materials Co. Ltd
- Product
- (R)-(+)-Propylene carbonate 16606-55-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-26
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- (R)-(+)-Propylene carbonate 16606-55-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-12-02
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