7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID

Product Name: 7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID
CAS No.: 90407-16-2
Chemical Name: 7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID
Synonyms: GA-0946;FS002044;7-chloro-2-benzothiophenecarboxylic acid;7-Chlorobenzothiophene-2-carboxylic acid;7-Chlorobenzo[b]thiophene-2-carboxylic acid;7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID;Benzo[b]thiophene-2-carboxylic acid, 7-chloro-;2-Carboxy-7-chlorobenzo[b]thiophene, 7-Chloro-1-benzothiophene-2-carboxylic acid
CBNumber: CB3792171
Molecular Formula: C9H5ClO2S
Formula Weight: 212.65
MOL File: 90407-16-2.mol

More

Less

7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID Property

Melting point:: 289-291
Boiling point:: 408.6±25.0 °C(Predicted)
Density: 1.546±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 3.27±0.30(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C9H5ClO2S/c10-6-3-1-2-5-4-7(9(11)12)13-8(5)6/h1-4H,(H,11,12)
InChIKey: AAXOHLXWCUMMQS-UHFFFAOYSA-N
SMILES: C12=C(Cl)C=CC=C1C=C(C(O)=O)S2

More

Less

Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2934999090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B418613
Product name: 7-Chloro-1-benzothiophene-2-carboxylicAcid
Packaging: 500mg
Price: $175
Updated: 2021/12/16

ChemScene

Product number: CS-M1618
Product name: Benzo[b]thiophene-2-carboxylicacid,7-chloro-
Purity: 99.27%
Packaging: 1g
Price: $52
Updated: 2021/12/16

Matrix Scientific

Product number: 047321
Product name: 7-Chloro-1-benzothiophene-2-carboxylic acid
Purity: >95%
Packaging: 1g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC135426
Product name: 7-Chloro-1-benzothiophene-2-carboxylic acid
Packaging: 250mg
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 6H21-5-X0
Product name: 7-Chlorobenzo[b]thiophene-2-carboxylic acid
Packaging: 1g
Price: $71
Updated: 2021/12/16

More

Less

7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

68-11-1

6334-18-5

90407-16-2

Step 1: Synthesis of 7-chloro-1-benzothiophene-2-carboxylic acid In a reaction flask containing potassium hydroxide (1.3 g, 22 mmol), 2-mercaptoacetic acid (0.70 mL, 10 mmol) and 10 mL of water, 2,3-dichlorobenzaldehyde (1.8 g, 10 mmol) was added. The reaction mixture was stirred at 120 °C for 2 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature and distilled water was added until the precipitated solid was completely dissolved. Subsequently, ether was added to the reaction solution and the mixture was separated into an organic layer and an aqueous layer. To the aqueous layer, 1.0 N hydrochloric acid was added dropwise to adjust the pH to 5, and then the aqueous layer was extracted with ethyl acetate. The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 7-chloro-1-benzothiophene-2-carboxylic acid (1.7 g, 82% yield) as a colorless liquid. The product was confirmed by 1H-NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI): 1H-NMR δ 7.48-7.54 (1H, m), 7.62-7.70 (1H, m), 7.98-8.04 (1H, m), 8.16-8.22 (1H, m); MS (ESI) [M+H]+ 213.

References

[1] Patent: US2014/128606, 2014, A1. Location in patent: Paragraph 0078; 0079; 0080; 0081; 0082; 0083

7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID Suppliers

China 74 India 1 United Kingdom 3 United States 8 Global 86

Chengdu Aofan Pharmtech Co.,Ltd

Tel: 15281070185; 13038283958
Email: 2865097598@qq.com
Country: China
ProdList: 111
Advantage: 55

Sichuan Fanzhijian Biomedical Technology Co., Ltd

Tel: 15281070185
Email: 2865097598@qq.com
Country: China
ProdList: 898
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Shanghai yirong biology science and technology co., ltd

Tel: 18049974220
Fax: +86 (21) 51062076
Email: 3060526242@qq.com
Country: China
ProdList: 995
Advantage: 60

Beijing Yisiyan Technology Research Center

Tel: 010-56645598 13366904824
Fax: 01062230033
Email: bjkaida@163.com
Country: China
ProdList: 1618
Advantage: 59

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

90407-16-2, 7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACIDRelated Search:

7-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID

7-Chlorobenzo[b]thiophene-2-carboxylic acid

7-Chlorobenzothiophene-2-carboxylic acid

Benzo[b]thiophene-2-carboxylic acid, 7-chloro-

2-Carboxy-7-chlorobenzo[b]thiophene, 7-Chloro-1-benzothiophene-2-carboxylic acid

7-chloro-2-benzothiophenecarboxylic acid

FS002044

GA-0946

90407-16-2