ChemicalBook > CAS DataBase List > 4-CHLORO-2-METHOXYBENZALDEHYDE

4-CHLORO-2-METHOXYBENZALDEHYDE

Product Name
4-CHLORO-2-METHOXYBENZALDEHYDE
CAS No.
53581-86-5
Chemical Name
4-CHLORO-2-METHOXYBENZALDEHYDE
Synonyms
2-Methoxy-4-chlorbenzaldehyd;4-CHLORO-2-METHOXYBENZALDEHYDE;2-Methoxy-4-chlorobenzaldehyde;4-Chloro1-formyl-2-methoxybenzene;Benzaldehyde, 4-chloro-2-methoxy-;4-Fluoro-4-(trifluoromethyl)phenacyl bromide
CBNumber
CB3801585
Molecular Formula
C8H7ClO2
Formula Weight
170.59
MOL File
53581-86-5.mol
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4-CHLORO-2-METHOXYBENZALDEHYDE Property

Melting point:
70-75°C
Boiling point:
268.8±20.0 °C(Predicted)
Density 
1.244±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
Appearance
Off-white to light yellow Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
WGK Germany 
3
HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H312Harmful in contact with skin

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
775959
Product name
4-Chloro-2-methoxybenzaldehyde
Purity
96%
Packaging
1g
Price
$92.6
Updated
2023/06/20
TRC
Product number
C428218
Product name
4-Chloro-2-methoxybenzaldehyde
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
C428218
Product name
4-Chloro-2-methoxybenzaldehyde
Packaging
500mg
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-5-0C
Product name
4-Chloro-2-methoxybenzaldehyde
Packaging
1g
Price
$120
Updated
2021/12/16
AK Scientific
Product number
7634AB
Product name
4-Chloro-2-methoxybenzaldehyde
Packaging
10g
Price
$250
Updated
2021/12/16
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4-CHLORO-2-METHOXYBENZALDEHYDE Chemical Properties,Usage,Production

Synthesis

61072-56-8

124-41-4

53581-86-5

The reaction was carried out with 2-fluoro-4-chlorobenzaldehyde (300 mg, 1.89 mmol) and sodium methanol (3784 μL, 1.89 mmol, methanol solution) with stirring at 50 °C for 3 hours. Upon completion of the reaction, the reaction mixture was concentrated to half of the original volume and subsequently purified by Biotage 25 column chromatography using 5% ethyl acetate/hexane as eluent to finally obtain 4-chloro-2-methoxybenzaldehyde (250 mg, 1.47 mmol, 77.5% yield).

References

[1] Patent: WO2009/158426, 2009, A1. Location in patent: Page/Page column 140
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 18, p. 5037 - 5041
[3] Angew. Chem., 2018, vol. 130, # 18, p. 5131 - 5135,5

4-CHLORO-2-METHOXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-2-METHOXYBENZALDEHYDE Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
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(1)02557626880
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China
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9ding chemical ( Shanghai) Limited
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Shanghai Fengchen Chem Co., Ltd.
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China
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SynAsst Chemical.
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021-60343070
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021-35122006
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
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China
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Xinyanhe Pharmatech Co.,Ltd
Tel
0519-85252752 15366845260
Fax
86-0519-85683352
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taihuaren@vip.163.com
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China
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View Lastest Price from 4-CHLORO-2-METHOXYBENZALDEHYDE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-CHLORO-2-METHOXYBENZALDEHYDE 53581-86-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-07-06