6-CHLORO-BENZOFURAN-3-ONE
- Product Name
- 6-CHLORO-BENZOFURAN-3-ONE
- CAS No.
- 3260-78-4
- Chemical Name
- 6-CHLORO-BENZOFURAN-3-ONE
- Synonyms
- 6-Chlorobenzofuran-3(2H)-one;6-BROMOBENZOFURAN-3(2H)-ONE;6-Bromo-3-Benzofuranone;6-CHLORO-BENZOFURAN-3-ONE;6-chloro-1-benzofuran-3-one;6-Chloro-3(2H)-benzofuranone;3(2H)-BENZOFURANONE, 5-BROMO-;3(2H)-Benzofuranone, 6-chloro-;6-CHLORO-2H-1-BENZOFURAN-3-ONE;6-chloro-2,3-dihydro-1-benzofuran-3-one
- CBNumber
- CB6495510
- Molecular Formula
- C8H5ClO2
- Formula Weight
- 168.58
- MOL File
- 3260-78-4.mol
6-CHLORO-BENZOFURAN-3-ONE Property
- Melting point:
- 123-123.5 °C
- Boiling point:
- 304.3±42.0 °C(Predicted)
- Density
- 1.428±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Yellow to brown Solid
- InChI
- InChI=1S/C8H5ClO2/c9-5-1-2-6-7(10)4-11-8(6)3-5/h1-3H,4H2
- InChIKey
- QSYZLDHZMYWEKL-UHFFFAOYSA-N
- SMILES
- O1C2=CC(Cl)=CC=C2C(=O)C1
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C381778
- Product name
- 6-Chlorobenzofuran-3(2H)-one
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 090530
- Product name
- 6-Chloro-3-benzofuranone
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $167
- Updated
- 2021/12/16
- Product number
- FC51275
- Product name
- 6-Chloro-Benzofuran-3-one
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- W5440
- Product name
- 6-Chloro-3-benzofuranone
- Packaging
- 1g
- Price
- $117
- Updated
- 2021/12/16
- Product number
- FC51275
- Product name
- 6-Chloro-Benzofuran-3-one
- Packaging
- 2g
- Price
- $364.4
- Updated
- 2021/12/16
6-CHLORO-BENZOFURAN-3-ONE Chemical Properties,Usage,Production
Chemical Properties
Orange Solid
Uses
6-Bromobenzofuran-3(2H)-one is a useful reactant for the preparation of tricyclic sulfones as RORγ modulators.
Synthesis
401622-26-2
3260-78-4
Step 3: 2-(carboxymethoxy)-4-chlorobenzoic acid (11.5 g, 50 mmol) obtained from step 2 was dissolved in acetic anhydride (100 ml) and anhydrous sodium acetate (10.0 g, excess) was added. The reaction mixture was heated to 150 °C and maintained for 4 hours. During the reaction, the color of the mixture changed to deep red. Upon completion of the reaction, the mixture was cooled to room temperature and quenched carefully with ice-cold water. The resulting red solid was collected by filtration and washed well with water. The washed red solid was suspended in 1N HCl and refluxed for 2 hours. After the reaction, 6-chlorobenzofuran-3(2H)-one precipitated from the mixture as a deep red solid. The product was isolated by filtration, washed well with water and dried at 40 °C and used in subsequent steps without further purification. Yield: 5.8 g (69%); MS data: (M + H): 169.
References
[1] Patent: US2009/54454, 2009, A1. Location in patent: Page/Page column 22
[2] Patent: WO2004/99191, 2004, A2. Location in patent: Page 49
[3] Patent: US2005/4162, 2005, A1. Location in patent: Page/Page column 12
6-CHLORO-BENZOFURAN-3-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-CHLORO-BENZOFURAN-3-ONE manufacturers
- Product
- 6-CHLORO-BENZOFURAN-3-ONE 3260-78-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-11
- Product
- 5-Bromobenzofuran-3-one 3260-78-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 50kgs/month
- Release date
- 2021-11-17