5-Bromo-1-benzofuran

Product Name: 5-Bromo-1-benzofuran
CAS No.: 23145-07-5
Chemical Name: 5-Bromo-1-benzofuran
Synonyms: 5-BROMOBENZOFURAN;5-Brombenzofuran;BUTTPARK 95\50-66;5-Bromobenzo[b]furan;5-BROMO-1-BENZOFURAN;Benzofuran, 5-broMo-;5-Bromobenzofuran ,97%;5-BROMOBENZO[BETA]FURAN;5-Bromobenzo[beta]furan, 98 %
CBNumber: CB9297481
Molecular Formula: C8H5BrO
Formula Weight: 197.03
MOL File: 23145-07-5.mol

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5-Bromo-1-benzofuran Property

Melting point:: 8°C(lit.)
Boiling point:: 226°C(lit.)
Density: 1.573 g/mL at 25 °C
refractive index: n20/D1.605
storage temp.: Sealed in dry,Room Temperature
form: liquid
color: Colourless to light yellow
InChI: InChI=1S/C8H5BrO/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5H
InChIKey: AYOVPQORFBWFNO-UHFFFAOYSA-N
SMILES: O1C2=CC=C(Br)C=C2C=C1
CAS DataBase Reference: 23145-07-5(CAS DataBase Reference)
EPA Substance Registry System: Benzofuran, 5-bromo- (23145-07-5)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-37/39
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 761796
Product name: 5-Bromobenzofuran
Purity: 97%
Packaging: 1g
Price: $100.1
Updated: 2025/07/31

TCI Chemical

Product number: B3889
Product name: 5-Bromobenzofuran
Purity: >97.0%(GC)
Packaging: 1g
Price: $50
Updated: 2025/07/31

TCI Chemical

Product number: B3889
Product name: 5-Bromobenzofuran
Purity: >97.0%(GC)
Packaging: 5g
Price: $149
Updated: 2025/07/31

TRC

Product number: B680355
Product name: 5-Bromobenzofuran
Packaging: 5g
Price: $195
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB153766
Product name: 5-Bromo-1-benzofuran
Packaging: 10g
Price: $275
Updated: 2021/12/16

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5-Bromo-1-benzofuran Chemical Properties,Usage,Production

Chemical Properties

Light yellow liquid

Uses

5-Bromobenzofuran is used in the synthesis of 1-(7-benzofuranyl)-4-methylpiperazine; a compound shown to bind strongly and with high selectivity to the serotonin receptor 5-HT2A in the presence of the receptor 5-HT7 in vitro.

Synthesis

112598-18-2

23145-07-5

The general procedure for the synthesis of 5-bromobenzofuran from 4-bromophenoxyacetaldehyde diethyl acetal was as follows: polyphosphoric acid (10 g) was added to a solution of benzene (50 mL), the product of step A (8.4 g). The reaction mixture was heated to reflux for 4 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and slowly poured into ice water (80 mL). The aqueous phase was extracted with ether and the organic phases were combined. The ether layer was washed sequentially with saturated sodium bicarbonate solution and brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 4.9 g of crude product in 85% yield.

References

[1] Patent: WO2004/33440, 2004, A1. Location in patent: Page 239-240
[2] Patent: US2004/147559, 2004, A1. Location in patent: Page 122
[3] Patent: US2004/106794, 2004, A1. Location in patent: Page 123
[4] Patent: WO2005/66147, 2005, A1. Location in patent: Page/Page column 209
[5] Patent: WO2005/68460, 2005, A1. Location in patent: Page/Page column 203

5-Bromo-1-benzofuran Preparation Products And Raw materials

Raw materials

Sodium hydride N,N-Dimethylformamide Sodium chloride Bromoacetaldehyde diethyl acetal Polyphosphoric acid Diethyl ether Benzene 4-Bromophenol Ethyl acetate Sodium bicarbonate Sodium hydroxide Magnesium sulfate PETROLEUM ETHER

Preparation Products

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5-Bromo-1-benzofuran Suppliers

Americas 1 Belgium 1 Canada 2 CHINA 229 Europe 1 France 3 Germany 3 India 19 Japan 2 Switzerland 1 United Kingdom 9 United States 28 Global 299

Zhejiang Zetian Fine Chemical Co., Ltd.

Tel: 0571-87682782 18957127338
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Email: sales@zetchem.com
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Hefei Shenghang Pharmaceutical Technology Co., Ltd.

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J & K SCIENTIFIC LTD.

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ITIC MEDCHEM(SUZHOU) CO.,LTD.

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
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View Lastest Price from 5-Bromo-1-benzofuran manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Bromo-1-benzofuran 23145-07-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-09

Shaanxi Dideu New Materials Co. Ltd

Product: 5-Bromo-1-benzofuran 23145-07-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-24

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Bromo-1-benzofuran 23145-07-5
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

23145-07-5, 5-Bromo-1-benzofuranRelated Search:

Benzofuran Furan 1,2-Dibromobenzene 4'-Bromopropiophenone 3-Bromoanisole 4-Bromofluorobenzene 2-Bromobenzonitrile 1,3-Dibromobenzene 5-BROMO-1-BENZOFURAN-2-CARBOXYLIC ACID Bromine 1-(5-BROMO-1-BENZOFURAN-2-YL)ETHANONE 3,5-DIBROMOBENZO[B]FURAN 6-CHLORO-BENZOFURAN-3-ONE 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID METHYL-7-BROMO-1-BENZOFURAN-2-CARBOXYLATE ethyl 2-(5-bromobenzofuran-3-yl)acetate 4-Fluoro-7-bromobenzofuran 5-BROMOBENZO[B]FURAN-2-CARBONYL CHLORIDE

5-BROMO-1-BENZOFURAN

5-BROMOBENZO[BETA]FURAN

5-BROMOBENZOFURAN

BUTTPARK 95\50-66

5-Bromobenzo[b]furan

5-Bromobenzo[beta]furan, 98 %

5-Bromobenzofuran ,97%

Benzofuran, 5-broMo-

5-Brombenzofuran

23145-07-5

C8H5BrO

pharmacetical