Mal-PEG2-Val-Cit-amido-PAB-OH

Product Name: Mal-PEG2-Val-Cit-amido-PAB-OH
CAS No.: 2055041-38-6
Chemical Name: Mal-PEG2-Val-Cit-amido-PAB-OH
Synonyms: Mal-PEG2-Val-Cit-PAB-OH;Mal-PEG2-Val-Cit-amido-PAB-OH;L-Ornithinamide, N-[3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
CBNumber: CB38054635
Molecular Formula: C29H42N6O9
Formula Weight: 618.68
MOL File: 2055041-38-6.mol

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Mal-PEG2-Val-Cit-amido-PAB-OH Property

Boiling point:: 948.4±65.0 °C(Predicted)
Density: 1.294±0.06 g/cm3(Predicted)
solubility: Soluble in DMSO, DMF
pka: 13.41±0.70(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23203
Product name: Mal-PEG2-Val-Cit-PAB-OH
Purity: 95%
Packaging: 50mg
Price: $380
Updated: 2021/12/16

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Mal-PEG2-Val-Cit-amido-PAB-OH Chemical Properties,Usage,Production

Description

Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The maleimide group is reactive toward thiol groups between pH 6.5 to 7.5. PEG chain increases the water solubility of the compound.

Uses

Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

IC 50

Cleavable Linker; Protease Cleavable Linker; PEGs

Mal-PEG2-Val-Cit-amido-PAB-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG2-Val-Cit-amido-PAB-OH Suppliers

China 23 United States 3 Global 26

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Aladdin Scientific

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Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
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MedChemExpress

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Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
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View Lastest Price from Mal-PEG2-Val-Cit-amido-PAB-OH manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG2-Val-Cit-PAB-OH 2055041-38-6
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-29

2055041-38-6, Mal-PEG2-Val-Cit-amido-PAB-OHRelated Search:

Mal-PEG2-alcohol 1,8-BIS-MALEIMIDOTRIETHYLENEGLYCOL Mal-PEG8-alcohol Mal-PEG8-amine TFA salt 1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Mal-PEG2-NHS ester Mal-PEG2-acid Mal-PEG2-CH2CH2COOtBu

Mal-PEG2-Val-Cit-amido-PAB-OH

Mal-PEG2-Val-Cit-PAB-OH

L-Ornithinamide, N-[3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

2055041-38-6

ADC LINKER