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Tisotumab

Product Name
Tisotumab
CAS No.
1418628-81-5
Chemical Name
Tisotumab
Synonyms
Tisotumab;1E10|||1.00E+10;Tisotumab (anti-F3);Research Grade Tisotumab;Research Grade Tisotumab(DHD00601)
CBNumber
CB38080959
Formula Weight
0
MOL File
Mol file
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Tisotumab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Tisotumab Chemical Properties,Usage,Production

Uses

Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody and ADC antibody. Tisotumab targets tissue factor (TF). Tisotumab can be used for the research of solid tumors[1].

in vivo

Tisotumab (DIG-labeled, infused) is delivered to the tumor tissue and then bound to the surface of HPAF-II tumors in HPAF-II tumor bearing mice[2].

References

[1] Coleman RL, et al. Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6): a multicentre, open-label, single-arm, phase 2 study. Lancet Oncol. 2021 May;22(5):609-619. DOI:10.1016/S1470-2045(21)00056-5
[2] Takao S, et al. Tissue factor targeted near-infrared photoimmunotherapy: a versatile therapeutic approach for malignancies. Cancer Immunol Immunother. 2025 Jan 3;74(2):48. DOI:10.1007/s00262-024-03903-2

Tisotumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Tisotumab Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
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TargetMol Chemicals Inc.
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Biolab Reagents
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Wuhan Jingkangen Biomedical Technology Co., Ltd
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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Changsha Fuzhen Biotechnology Co.,LTD
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Atagenix Laboratories
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AntibodySystem Laboratories SAS
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Biosynth Biological Technology (Suzhou) Co Ltd
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Cell Sciences
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Biorbyt Ltd.
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Proteintech China
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