Synthesis
ChemicalBook > CAS DataBase List > 4-Bromobenzo[b]thiophene

4-Bromobenzo[b]thiophene

Synthesis
Product Name
4-Bromobenzo[b]thiophene
CAS No.
5118-13-8
Chemical Name
4-Bromobenzo[b]thiophene
Synonyms
4-Bromobenzothiophene;4-BROMO-1-BENZOTHIOPHENE;4-bromo-thiophene;4-Bromothianaphthene;5-cyanobenzothiophene;Bromobenzo[b]thiophene;4-BROMO-BENZO[B]THIOPHENE;Brexpiprazole intermdiate;Benzo[b]thiophene,4-broMo-;CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE
CBNumber
CB3813658
Molecular Formula
C8H5BrS
Formula Weight
213.09
MOL File
5118-13-8.mol
More
Less

4-Bromobenzo[b]thiophene Property

Boiling point:
144 °C(Press: 20 Torr)
Density 
1.649±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
solid
color 
White to off-white
InChI
InChI=1S/C8H5BrS/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H
InChIKey
QPBSEYFVZDMBFW-UHFFFAOYSA-N
SMILES
C12=CC=CC(Br)=C1C=CS2
More
Less

Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B680503
Product name
4-Bromo-benzo[b]thiophene
Packaging
1g
Price
$75
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B1950
Product name
4-Bromobenzo[b]thiophene
Purity
95%
Packaging
1g
Price
$8
Updated
2021/12/16
AK Scientific
Product number
J97401
Product name
4-Bromobenzo[b]thiophene
Packaging
1g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
122176
Product name
4-Bromobenzothiophene
Purity
90+%
Packaging
1g
Price
$10
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B1950
Product name
4-Bromobenzo[b]thiophene
Purity
95%
Packaging
5g
Price
$20
Updated
2021/12/16
More
Less

4-Bromobenzo[b]thiophene Chemical Properties,Usage,Production

Synthesis

The traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene. 

Uses

4-Bromobenzo[b]thiophene is an important intermediate in the drug ipiprazole for the treatment of schizophrenia.

4-Bromobenzo[b]thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Bromobenzo[b]thiophene Suppliers

Canada 1 China 265 India 8 United Kingdom 4 United States 19 Global 297
R&D Scientific Inc.
Tel
+1-2266000236
Email
sales@rdscientific.com
Country
Canada
ProdList
1628
Advantage
58
More
Less

View Lastest Price from 4-Bromobenzo[b]thiophene manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2-5 MTs
Release date
2024-05-11
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-06
R&D Scientific Inc.
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $2200.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-04-26

5118-13-8, 4-Bromobenzo[b]thiopheneRelated Search:

4-BROMO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID Thianaphthene Brexpiprazole-d8 4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butan-1-ol 4-BROMO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Brexpiprazole Impurity 20 Brexpiprazole Impurity 36 Brexpiprazole Impurity 5 HCl Brexpiprazole Impurity 2 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one Brexpiprazole Impurity 7 Brexpiprazole Impurity 18 Brexpiprazole Impurity 24 Brexpiprazole Impurity 22 (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE Brexpiprazole Impurity 21 8-(benzo[b]thiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride 5-HYDROXY-2(1H)-QUINOLINONE

  • 4-BROMO-BENZO[B]THIOPHENE
  • 4-Bromobenzothiophene
  • 4-BROMO-1-BENZOTHIOPHENE
  • 4-Bromothianaphthene
  • 5-cyanobenzothiophene
  • 4-bromo-thiophene
  • Benzo[b]thiophene,4-broMo-
  • 4-Bromo-1-benzothiophene, 4-Bromothianaphthene
  • 4-BROMO-BENZO[B]THIOPHENE ISO 9001：2015 REACH
  • Brexpiprazole intermdiate
  • CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE
  • Bromobenzo[b]thiophene
  • Brexpiprazole Impurity 13 4-Bromo benzo[b]thiophene
  • 5118-13-8
  • Benzothiophene
  • Halogenated
  • Organohalides