Synthesis
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4-Bromobenzo[b]thiophene

Synthesis
Product Name
4-Bromobenzo[b]thiophene
CAS No.
5118-13-8
Chemical Name
4-Bromobenzo[b]thiophene
Synonyms
4-Bromobenzothiophene;4-BROMO-1-BENZOTHIOPHENE;4-bromo-thiophene;4-Bromothianaphthene;5-cyanobenzothiophene;Bromobenzo[b]thiophene;4-BROMO-BENZO[B]THIOPHENE;Brexpiprazole intermdiate;Benzo[b]thiophene,4-broMo-;CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE
CBNumber
CB3813658
Molecular Formula
C8H5BrS
Formula Weight
213.09
MOL File
5118-13-8.mol
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4-Bromobenzo[b]thiophene Property

Boiling point:
144 °C(Press: 20 Torr)
Density 
1.649±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
solid
color 
White to off-white
InChI
InChI=1S/C8H5BrS/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H
InChIKey
QPBSEYFVZDMBFW-UHFFFAOYSA-N
SMILES
C12=CC=CC(Br)=C1C=CS2
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B680503
Product name
4-Bromo-benzo[b]thiophene
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
122176
Product name
4-Bromobenzothiophene
Purity
90+%
Packaging
25g
Price
$84
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB57657
Product name
4-Bromobenzo[b]thiophene
Packaging
1g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB57657
Product name
4-Bromobenzo[b]thiophene
Packaging
2g
Price
$150
Updated
2021/12/16
SynQuest Laboratories
Product number
5H66-9-X5
Product name
4-Bromobenzo[b]thiophene
Packaging
25g
Price
$160
Updated
2021/12/16
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4-Bromobenzo[b]thiophene Chemical Properties,Usage,Production

Synthesis

The traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene. 

Uses

4-Bromobenzo[b]thiophene is an important intermediate in the drug ipiprazole for the treatment of schizophrenia.

4-Bromobenzo[b]thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromobenzo[b]thiophene Suppliers

Canada 1 China 268 India 8 United Kingdom 4 United States 19 Global 300
Noble Molecular Research
Tel
--
Fax
--
Country
India
ProdList
53
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 4-Bromobenzo[b]thiophene manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-06
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2-5 MTs
Release date
2024-05-11
R&D Scientific Inc.
Product
4-Bromobenzo[b]thiophene 5118-13-8
Price
US $2200.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-04-26

5118-13-8, 4-Bromobenzo[b]thiopheneRelated Search:

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  • 4-BROMO-BENZO[B]THIOPHENE
  • 4-Bromobenzothiophene
  • 4-BROMO-1-BENZOTHIOPHENE
  • 4-Bromothianaphthene
  • 5-cyanobenzothiophene
  • 4-bromo-thiophene
  • Benzo[b]thiophene,4-broMo-
  • 4-Bromo-1-benzothiophene, 4-Bromothianaphthene
  • 4-BROMO-BENZO[B]THIOPHENE ISO 9001：2015 REACH
  • Brexpiprazole intermdiate
  • CAS5118-13-8 4-BROMO-BENZO[B]THIOPHENE
  • Bromobenzo[b]thiophene
  • Brexpiprazole Impurity 13 4-Bromo benzo[b]thiophene
  • 5118-13-8
  • Benzothiophene
  • Halogenated
  • Organohalides