ChemicalBook > CAS DataBase List > 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
- Product Name
- 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
- CAS No.
- 180046-99-5
- Chemical Name
- 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
- Synonyms
- SDZ NKT 343;1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE;L-Alaninamide, 1-[[(2-nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-
- CBNumber
- CB3839272
- Molecular Formula
- C33H33N5O5
- Formula Weight
- 579.65
- MOL File
- 180046-99-5.mol
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1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Property
- Boiling point:
- 892.8±65.0 °C(Predicted)
- Density
- 1.327±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- form
- Powder
- pka
- 11.66±0.70(Predicted)
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N-Bromosuccinimide Price
Tocris
- Product number
- 2394
- Product name
- SDZNKT343
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $241
- Updated
- 2021/12/16
Usbiological
- Product number
- 256646
- Product name
- SDZ NKT 343
- Packaging
- 10mg
- Price
- $588
- Updated
- 2021/12/16
TRC
- Product number
- S211123
- Product name
- SDZNKT343
- Packaging
- 10mg
- Price
- $175
- Updated
- 2021/12/16
TRC
- Product number
- S211123
- Product name
- SDZNKT343
- Packaging
- 50mg
- Price
- $795
- Updated
- 2021/12/16
TRC
- Product number
- S211123
- Product name
- SDZNKT343
- Packaging
- 100mg
- Price
- $1400
- Updated
- 2021/12/16
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1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Chemical Properties,Usage,Production
Uses
SDZ NKT 343 is a potent human NK1 tachykinin receptor antagonist.
Biological Activity
Highly selective human tachykinin NK 1 receptor antagonist (IC 50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK 2 and NK 3 receptors. Potently antagonizes SP-induced Ca 2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo .
storage
Store at +4°C
1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77
- Tel
- --
- Fax
- --
- sales@carbonesci.com
- Country
- United Kingdom
- ProdList
- 6666
- Advantage
- 30
180046-99-5, 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDERelated Search:
PYRROLIDINE-1-CARBOXYLIC ACID AMIDE
1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE