2-PYRAZOL-1-YL-PYRIDINE

Product Name: 2-PYRAZOL-1-YL-PYRIDINE
CAS No.: 25700-11-2
Chemical Name: 2-PYRAZOL-1-YL-PYRIDINE
Synonyms: 2-pyrazole-1-pyridine;2-(1-Pyrazolyl)pyridine;2-PYRAZOL-1-YL-PYRIDINE;2-(1-Pyrazolyl)pyridine >2-(1H-pyrazol-1-yl)pyridine;Pyridine, 2-(1H-pyrazol-1-yl)-
CBNumber: CB3840494
Molecular Formula: C8H7N3
Formula Weight: 145.16
MOL File: 25700-11-2.mol

More

Less

2-PYRAZOL-1-YL-PYRIDINE Property

Melting point:: 37.0 to 41.0 °C
Boiling point:: 265.6±13.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to lump
pka: 2.83±0.10(Predicted)
color: White to Almost white
InChIKey: XXTPHXNBKRVYJI-UHFFFAOYSA-N

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: P2239
Product name: 2-(1-Pyrazolyl)pyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $93
Updated: 2025/07/31

TCI Chemical

Product number: P2239
Product name: 2-(1-Pyrazolyl)pyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $320
Updated: 2025/07/31

TRC

Product number: B529850
Product name: 2-(1H-Pyrazol-1-yl)pyridine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: 8520AD
Product name: 2-(1H-Pyrazol-1-yl)pyridine
Packaging: 1g
Price: $117
Updated: 2021/12/16

Matrix Scientific

Product number: 101724
Product name: 2-(1H-Pyrazol-1-yl)pyridine
Purity: 95%
Packaging: 1g
Price: $188
Updated: 2021/12/16

More

Less

2-PYRAZOL-1-YL-PYRIDINE Chemical Properties,Usage,Production

Synthesis

288-13-1

109-04-6

25700-11-2

General procedure for the synthesis of 2-pyrazole-1-pyridine (Pyr-N-PzH) from pyrazole and 2-bromopyridine: To a 250 mL single-necked round-bottomed flask were added 15.0 g (95 mmol) of 2-bromopyridine, 25.0 g (367 mmol, 3.86 equiv) of pyrazole and 45 mL of xylene. The reaction mixture was heated to reflux for 8 hours and subsequently cooled to room temperature. The resulting mixture was dissolved in dichloromethane and the organic layer was washed four times with 250 mL of water (until pyrazole was not detected by gas chromatography). The organic layer was dried over anhydrous magnesium sulfate, filtered and rotary evaporated to give 12.0 g (82.6 mmol, 87% yield) of the target product as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.59 (m, 1H, pyridinyl 6-H), 8.39 (s, 1H, pyrazol-5-H), 7.90 (d, 1H, pyridinyl 3-H), 7.80 (m, 1H, pyridinyl 4-H), 7.73 (s, 1H, pyrazol 3-H), 7.15 (s, 1H, pyridinyl -5-H), 6.45 (m, 1H, pyrazole-4-H).

References

[1] Tetrahedron, 2010, vol. 66, # 47, p. 9141 - 9144
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 13, p. 4101 - 4114
[3] European Journal of Organic Chemistry, 2011, # 14, p. 2692 - 2696
[4] Journal of Organic Chemistry, 2005, vol. 70, # 13, p. 5164 - 5173
[5] Journal of Organic Chemistry, 2011, vol. 76, # 2, p. 654 - 660

2-PYRAZOL-1-YL-PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-PYRAZOL-1-YL-PYRIDINE Suppliers

China 64 India 2 Japan 1 United Kingdom 1 United States 9 Global 77

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Springchem New Material Technology Co.,Limited

Tel: +86-021-62885108 +8613917661608
Email: info@spring-chem.com
Country: China
ProdList: 2068
Advantage: 57

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4720
Advantage: 55

Chem-Stone Co.,Ltd.

Tel: 020-82185713,82185709 13418171485
Fax: 020-82185696
Email: sales@chem-stone.com
Country: China
ProdList: 744
Advantage: 56

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Changsha Luxing Bio-Chem Technology Co., Ltd.

Tel: 0731-88827538 15873153880
Fax: 0731-88827238
Email: luxingbc@126.com
Country: China
ProdList: 1995
Advantage: 65

Shanghai Tombiopharma Chemical Co. Ltd.

Tel: 13391076197
Email: tombiopharma@163.com
Country: China
ProdList: 4987
Advantage: 55

25700-11-2, 2-PYRAZOL-1-YL-PYRIDINERelated Search:

6-(1H-Pyrazol-1-yl)nicotinic acid Methyl 6-(1H-pyrazol-1-yl)pyridine-3-carboxylate 5-amino-1-(pyridin-2-yl)-1H-pyrazole-4-carbonitrile 1-(6-FLUORO-2-PYRIDINYL)-4-PHENYL-1H-PYRAZOL-3-AMINE N-(4-METHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE N-(3-METHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE 1-(6-CHLORO-2-PYRIDINYL)-N-METHYL-4-NITRO-1H-PYRAZOL-5-AMINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE 7-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-2,4-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE 1-[5-methyl-1-(pyridin-2-yl)-1H-pyrazol-4-yl]ethan-1-one N-METHYL-4-NITRO-1-(2-PYRIDINYL)-1H-PYRAZOL-5-AMINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-PHENYL-1H-PYRAZOL-5-AMINE 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-(4-FLUOROPHENYL)-1H-PYRAZOL-5-AMINE N-(2-METHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE 2-FLUORO-6-(3-PHENYL-1H-PYRAZOL-1-YL)PYRIDINE N-(2,5-DIMETHOXYPHENYL)-6-(1H-PYRAZOL-1-YL)NICOTINAMIDE 2-FLUORO-6-[3-(4-METHOXYPHENYL)-1H-PYRAZOL-1-YL]PYRIDINE

2-PYRAZOL-1-YL-PYRIDINE

2-(1H-pyrazol-1-yl)pyridine

2-(1-Pyrazolyl)pyridine

2-(1-Pyrazolyl)pyridine &gt

Pyridine, 2-(1H-pyrazol-1-yl)-

2-pyrazole-1-pyridine

25700-11-2