(S)-1-PHENYL-BUT-3-EN-1-OL
Synthesis
- Product Name
- (S)-1-PHENYL-BUT-3-EN-1-OL
- CAS No.
-
77118-87-7
- Chemical Name
- (S)-1-PHENYL-BUT-3-EN-1-OL
- Synonyms
- (1S)-1-phenylbut-3-en-1-ol;(S)-1-PHENYL-BUT-3-EN-1-OL;Benzenemethanol, α-2-propen-1-yl-, (αS)-
- CBNumber
- CB3846542
- Molecular Formula
- C10H12O
- Formula Weight
- 148.2
- MOL File
- 77118-87-7.mol
Hazard and Precautionary Statements (GHS)
N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CCH0001895
- Product name
- (S)-1-PHENYL-BUT-3-EN-1-OL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.86
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CCH0001895
- Product name
- (S)-1-PHENYL-BUT-3-EN-1-OL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $2905.35
- Updated
- 2021/12/16
JR MediChem
- Product number
- JR01-C008
- Product name
- (S)-1-phenylbut-3-en-1-ol
- Purity
- 96%
- Packaging
- 1g
- Price
- $268
- Updated
- 2021/12/16
(S)-1-PHENYL-BUT-3-EN-1-OL Chemical Properties,Usage,Production
Synthesis
To a solution of the bis-phosphoramide catalyst (59 mg, 0.1 mmol) in CH2Cl2 (1 mL) and diisopropylethylamine (1.0 mL) under N2 at −78 °C was added allyltrichlorosilane (580 µL, 4.0 mmol). The solution was stirred at −78 °C for 10 min before benzaldehyde (200 mL, 2.0 mmol) was added. The resulting mixture was stirred at this temperature for 8 h whereupon the cold solution was poured in to a mixture of saturated aqueous NaHCO3 (10 mL) and saturated aqueous KF (10 mL) at 0 °C with vigorous stirring. The mixture was stirred for 2 h at room temperature and then fifiltered through Celite. The layers were then separated and the aqueous layer was extracted with CH2Cl2 (3 × 30 mL). The combined organic extracts were dried (MgSO4), fifiltered, and concentrated. The oily residue was purifified by column chromatography (silica gel) eluting with CH2Cl2:pentane (3:1) followed by CH2Cl2 to give 254 mg (85%) of the benzylic alcohol in 87% ee. Reference: Denmark, S. E.; Fu, J. J. Am. Chem. Soc. 2001, 123, 9488−9489
(S)-1-PHENYL-BUT-3-EN-1-OL Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-1-PHENYL-BUT-3-EN-1-OL Suppliers
- Tel
- --
- Fax
- --
- Email
- sales@allichemllc.com
- Country
- United States
- ProdList
- 6516
- Advantage
- 60
- Tel
- --
- Fax
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- Email
- sales@betapharma.com
- Country
- United States
- ProdList
- 6226
- Advantage
- 60
- Tel
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- Fax
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- Email
- sales@apacpharma.com
- Country
- United States
- ProdList
- 6322
- Advantage
- 38
- Tel
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- Fax
- --
- Email
- sales@chempacific.com
- Country
- United States
- ProdList
- 6891
- Advantage
- 51
77118-87-7, (S)-1-PHENYL-BUT-3-EN-1-OLRelated Search:
(S)-1-PHENYL-BUT-3-EN-1-OL
(1S)-1-phenylbut-3-en-1-ol
Benzenemethanol, α-2-propen-1-yl-, (αS)-
77118-87-7