IRALUKAST

Product Name: IRALUKAST
CAS No.: 151581-24-7
Chemical Name: IRALUKAST
Synonyms: Unii-L1E28E0J8f;Iralukast [inn];Iralukast (CGP 45715A);7-[(2S,3E,5Z)-10-(4-Acetyl-3-Hydroxy-2-Propylphenoxy)-1-Hydroxy-1-[3-(Trifluoromethyl)Phenyl]Deca-3,5-Dien-2-Yl]Sulfanyl-4-Oxochromene-2-Carboxylic Acid;4H-1-Benzopyran-2-carboxylic acid, 7-[[(1S,2E,4Z)-9-(4-acetyl-3-hydroxy-2-propylphenoxy)-1-[(R)-hydroxy[3-(trifluoromethyl)phenyl]methyl]-2,4-nonadien-1-yl]thio]-4-oxo-
CBNumber: CB52446414
Molecular Formula: C38H37F3O8S
Formula Weight: 710.76
MOL File: 151581-24-7.mol

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IRALUKAST Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: INB0004252
Product name: IRALUKAST
Purity: 95.00%
Packaging: 5MG
Price: $495.17
Updated: 2021/12/16

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IRALUKAST Chemical Properties,Usage,Production

Uses

Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.

IC 50

CysLT₁: 7.8 (pKi)

References

[1] Magnus B?ck, et al. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. Br J Pharmacol. 2014 Aug; 171(15): 3551–3574. DOI:10.1111/bph.12665
[2] Valérie Capra, et al. Pharmacological characterization of the cysteinyl-leukotrieneantagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro.Br J Pharmacol. 1998 Feb; 123(3): 590–598. DOI:10.1038/sj.bjp.0701636

IRALUKAST Preparation Products And Raw materials

Raw materials

Preparation Products

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IRALUKAST Suppliers

China 8 Global 8

ShangHai Caerulum Pharma Discovery Co., Ltd.

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151581-24-7, IRALUKASTRelated Search:

4-(ETHYLTHIO)BENZALDEHYDE 2-Formylphenoxyacetic acid (S)-1-[3-(TRIFLUOROMETHYL)PHENYL]ETHANOL IRALUKAST 1-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOL-1 3-[4-(METHYLTHIO)PHENYL]-1-PROPENE ALPHA-METHYL-3-(TRIFLUOROMETHYL)BENZYL ALCOHOL (S)-1-PHENYL-BUT-3-EN-1-OL 3-[4-(ETHYLTHIO)PHENYL]-1-PROPENE 4-[(3-TRIFLUOROMETHYL)PHENYL]-1-BUTENE

Iralukast [inn]

Unii-L1E28E0J8f

7-[(2S,3E,5Z)-10-(4-Acetyl-3-Hydroxy-2-Propylphenoxy)-1-Hydroxy-1-[3-(Trifluoromethyl)Phenyl]Deca-3,5-Dien-2-Yl]Sulfanyl-4-Oxochromene-2-Carboxylic Acid

4H-1-Benzopyran-2-carboxylic acid, 7-[[(1S,2E,4Z)-9-(4-acetyl-3-hydroxy-2-propylphenoxy)-1-[(R)-hydroxy[3-(trifluoromethyl)phenyl]methyl]-2,4-nonadien-1-yl]thio]-4-oxo-

Iralukast (CGP 45715A)

151581-24-7

C38H37F3O8S