paraflutizide
- Product Name
- paraflutizide
- CAS No.
- 1580-83-2
- Chemical Name
- paraflutizide
- Synonyms
- LD-3612;Paraflutizida;paraflutizide;6-Chloro-3-(p-fluorobenzyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;6-chloro-3-(4-fluorobenzyl)-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-chloro-3-[(4-fluorophenyl)methyl]-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[(4-fluorophenyl)methyl]-3,4-dihydro-, 1,1-dioxide
- CBNumber
- CB3875049
- Molecular Formula
- C14H13ClFN3O4S2
- Formula Weight
- 405.85
- MOL File
- 1580-83-2.mol
paraflutizide Property
- Melting point:
- 238-240°
- Boiling point:
- 636.2±65.0 °C(Predicted)
- Density
- 1.571±0.06 g/cm3(Predicted)
- pka
- 8.66±0.40(Predicted)
Safety
- Toxicity
- LD50 oral in mouse: > 10gm/kg
N-Bromosuccinimide Price
- Product number
- API0012179
- Product name
- PARAFLUTIZIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.47
- Updated
- 2021/12/16
paraflutizide Chemical Properties,Usage,Production
Originator
Paraflutizide, Shanghai Lansheng
Manufacturing Process
A mixture of 5.0 g (0.0357 g/mol) of ρ-fluorophenylethyl alcohol, 2.0 g (0.007 g/mol) of 5-chloro-2,4-disulphamylaniline, 2.0 g (0.0068 g/mol) of potassium bichromate and 15 ml of concentrated hydrochloric acid (0.176 g/mol) and 25 ml of water is heated under reflux for 1 h. The mixture is allowed to cool, and 15 ml of ether are added to separate the excess of ρ-fluorophenylethyl alcohol. The aqueous layer is decanted and frozen for 2 h and the precipitate is separated, washed with water and dried in vacuum over phosphoric anhydride. There are collected 1.35 g (yield 47.5%) of the 1,1-dioxide of 3-ρfluorophenyl-methyl-7-sulphamyl-6-chloro-3,4-dihydrobenzo-1,2,4-thiadiazine, which when recrystallised from 30 ml of 50% alcohol on "Norit" active carbon takes the form of a white crystalline substance, melting point is 239°C.
Therapeutic Function
Diuretic
paraflutizide Preparation Products And Raw materials
Raw materials
Preparation Products
paraflutizide Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74