ChemicalBook > CAS DataBase List > Tritiozine
Tritiozine
- Product Name
- Tritiozine
- CAS No.
- 35619-65-9
- Chemical Name
- Tritiozine
- Synonyms
- Tresanil;ISF-2001;Tritiozine;Tritiozina;Sulmetozine;trithiozine;Tritiozinum;Tritiozine USP/EP/BP;4-(3,4,5-Trimethoxythiobenzoyl)morpholine;morpholino-(3,4,5-trimethoxyphenyl)methanethione
- CBNumber
- CB3875261
- Molecular Formula
- C14H19NO4S
- Formula Weight
- 297.37
- MOL File
- 35619-65-9.mol
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Tritiozine Property
- Melting point:
- 141-143°
- Boiling point:
- 420.8±55.0 °C(Predicted)
- Density
- 1.2461 (rough estimate)
- refractive index
- 1.7500 (estimate)
- pka
- 0.88±0.20(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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Safety
- Toxicity
- LD50 i.p. in mice: 2000 mg/kg (Pifferi, 1973)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0011984
- Product name
- MORPHOLIN-4-YL-(3,4,5-TRIMETHOXY-PHENYL)-METHANETHIONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.21
- Updated
- 2021/12/16
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Tritiozine Chemical Properties,Usage,Production
Uses
Trithiozine is an orally active antisecretory and antiulcer agent. Trithiozine can be used for the research of peptic ulcer disease and hypersecretory disorders[1].
Definition
ChEBI: Tritiozine is a member of methoxybenzenes.
in vivo
Trithiozine (T) (i. p., oral, i. v.; 50 mg/kg, 200 mg/kg) shows a considerable antisecretory and antiulcer activity on different experimental models in the rats and dogs[1].
| Animal Model: | female Sprague-Dawley rats and male beagle dogs[1] |
| Dosage: | 50 mg/kg (rats); 200 mg/kg or 50 mg/kg (dogs) |
| Administration: | i. p., single (rats); oral, single or i. v. (dogs) |
| Result: | Showed an apparent plasma half-life of about 2.5 h in rats and 1 h in dogs and rapidly metabolized yielding two metabolites and two conjugates. |
References
[1] G. M. Pacifici, et al. Pharmacokinetics and biotransformation, in rats and dogs, of trithiozine, a new antisecretory drug. , 1(3), 141–147. doi:10.1007/bf03189268.
Tritiozine Preparation Products And Raw materials
Raw materials
Preparation Products
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