ChemicalBook > CAS DataBase List > (±)-4-aminohex-5-enoic acid

(±)-4-aminohex-5-enoic acid

Product Name: (±)-4-aminohex-5-enoic acid
CAS No.: 68506-86-5
Chemical Name: (±)-4-aminohex-5-enoic acid
Synonyms: CPP 109;(±)-Vigabatrin;rac-Vigabatrin;(+/-)-Vigabatrin;Vigabatrin (1712001);SABRIL; Γ-VINYL-GABA;5-Hexenoic acid, 4-amino-;13C,D5-rac-Vigabatrin HCL;()-4-aminohex-5-enoic acid;(±)-4-aminohex-5-enoic acid
CBNumber: CB3877472
Molecular Formula: C6H11NO2
Formula Weight: 129.16
MOL File: 68506-86-5.mol

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(±)-4-aminohex-5-enoic acid Property

Melting point:: 209℃
Boiling point:: 277.7±28.0 °C(Predicted)
Density: 1.064±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Methanol (Slightly), Water (Slightly)
pka: 4.36±0.10(Predicted)
form: Solid
color: Off-White
Water Solubility: Soluble to 100 mM in water

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: MP7745000
HS Code: 2922498050
Hazardous Substances Data: 68506-86-5(Hazardous Substances Data)
Toxicity: LD50 oral in rat: 3gm/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001400
Product name: Vigabatrin
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10 mg
Price: $118
Updated: 2025/07/31

Sigma-Aldrich

Product number: V8261
Product name: (±)-Vigabatrin
Packaging: 10mg
Price: $120
Updated: 2025/07/31

Sigma-Aldrich

Product number: V8261
Product name: (±)-Vigabatrin
Packaging: 50mg
Price: $464.55
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR3429
Product name: Vigabatrin
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 400MG
Price: $339
Updated: 2025/07/31

Sigma-Aldrich

Product number: 5.05989
Product name: Vigabatrin - CAS 68506-86-5 - Calbiochem
Packaging: 10MG
Price: $93.5
Updated: 2025/07/31

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(±)-4-aminohex-5-enoic acid Chemical Properties,Usage,Production

Uses

rac-Vigabatrin a novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.

Definition

ChEBI: Vigabatrin is a gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase It has a role as an anticonvulsant and an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor.

Biochem/physiol Actions

Irreversible GABA transaminase inhibitor. Increases intracellular concentration of GABA in nerve endings; possesses antiepileptic activity.

in vivo

A significant increase in seizure threshold is observed following systemic (i.p.) administration of high (600 or 1200 mg/kg) doses of Vigabatrin. Bilateral microinjection of Vigabatrin (10 μg) into either the anterior or posterior substantia nigra pars reticulata (SNr) also increased seizure threshold, but less markedly than systemic treatment. Focal delivery into the subthalamic nucleus (STN) increased seizure threshold more markedly than either intranigral or systemic administration of Vigabatrin^[1].

storage

Store at +4°C

(±)-4-aminohex-5-enoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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68506-86-5, (±)-4-aminohex-5-enoic acidRelated Search:

OLEIC ACID-1-13C BUTYL OLEATE Aspartate aminotransferase EPA Eicosenoic acid Vigabatrin EP Impurity F 2-(2-aminobut-3-enyl)propanedioic acid 4-Aminobutyric acid Vigabatrin EP Impurity B 5-Vinylpyrrolidone VIGABATRIN

(±)-4-aminohex-5-enoic acid

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SABRIL; Γ-VINYL-GABA

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(+/-)-Vigabatrin

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rac-Vigabatrin

(±)-Vigabatrin

()-4-aminohex-5-enoic acid

(±)-4-aminohex-5-enoic acid

γ-Vinyl-GABA (4-Aminohexenoic acid) 97%min

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13C,D5-rac-Vigabatrin HCL

68506-86-5