(±)-4-aminohex-5-enoic acid
- Product Name
- (±)-4-aminohex-5-enoic acid
- CAS No.
- 68506-86-5
- Chemical Name
- (±)-4-aminohex-5-enoic acid
- Synonyms
- CPP 109;(±)-Vigabatrin;rac-Vigabatrin;(+/-)-Vigabatrin;Vigabatrin (1712001);SABRIL; Γ-VINYL-GABA;5-Hexenoic acid, 4-amino-;13C,D5-rac-Vigabatrin HCL;()-4-aminohex-5-enoic acid;(±)-4-aminohex-5-enoic acid
- CBNumber
- CB3877472
- Molecular Formula
- C6H11NO2
- Formula Weight
- 129.16
- MOL File
- 68506-86-5.mol
(±)-4-aminohex-5-enoic acid Property
- Melting point:
- 209℃
- Boiling point:
- 277.7±28.0 °C(Predicted)
- Density
- 1.064±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Methanol (Slightly), Water (Slightly)
- pka
- 4.36±0.10(Predicted)
- form
- Solid
- color
- Off-White
- Water Solubility
- Soluble to 100 mM in water
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- MP7745000
- HS Code
- 2922498050
- Hazardous Substances Data
- 68506-86-5(Hazardous Substances Data)
- Toxicity
- LD50 oral in rat: 3gm/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P314Get medical advice/attention if you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Y0001400
- Product name
- Vigabatrin
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 10 mg
- Price
- $118
- Updated
- 2025/07/31
- Product number
- V8261
- Product name
- (±)-Vigabatrin
- Packaging
- 10mg
- Price
- $120
- Updated
- 2025/07/31
- Product number
- V8261
- Product name
- (±)-Vigabatrin
- Packaging
- 50mg
- Price
- $464.55
- Updated
- 2025/07/31
- Product number
- PHR3429
- Product name
- Vigabatrin
- Purity
- certified reference material, pharmaceutical secondary standard
- Packaging
- 400MG
- Price
- $339
- Updated
- 2025/07/31
- Product number
- 5.05989
- Product name
- Vigabatrin - CAS 68506-86-5 - Calbiochem
- Packaging
- 10MG
- Price
- $93.5
- Updated
- 2025/07/31
(±)-4-aminohex-5-enoic acid Chemical Properties,Usage,Production
Uses
rac-Vigabatrin a novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.
Definition
ChEBI: Vigabatrin is a gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase It has a role as an anticonvulsant and an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor.
Biochem/physiol Actions
Irreversible GABA transaminase inhibitor. Increases intracellular concentration of GABA in nerve endings; possesses antiepileptic activity.
in vivo
A significant increase in seizure threshold is observed following systemic (i.p.) administration of high (600 or 1200 mg/kg) doses of Vigabatrin. Bilateral microinjection of Vigabatrin (10 μg) into either the anterior or posterior substantia nigra pars reticulata (SNr) also increased seizure threshold, but less markedly than systemic treatment. Focal delivery into the subthalamic nucleus (STN) increased seizure threshold more markedly than either intranigral or systemic administration of Vigabatrin[1].
storage
Store at +4°C
(±)-4-aminohex-5-enoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(±)-4-aminohex-5-enoic acid Suppliers
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