ChemicalBook > CAS DataBase List > 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride

6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride

Product Name
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride
CAS No.
56776-32-0
Chemical Name
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride
Synonyms
StresaM;Etifoxine HCl;HOE-36801 hydrochloride;Etifoxine·hydrochloride;Etifoxine HCl (HOE-36801);NSC 163501;ANTIBIOTIC AT-125;U 42126;2-EthylaMino-6-chloro-4-Methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride;6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride;6-Chloro-N-ethyl-4-Methyl-4-phenyl-4H-3,1-benzoxazin-2-aMine Hydrochloride;6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminehydrochloride
CBNumber
CB3883790
Molecular Formula
C17H18Cl2N2O
Formula Weight
337.24362
MOL File
56776-32-0.mol
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6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Property

Melting point:
ND
storage temp. 
-20°C
solubility 
DMSO: ≥5mg/mL
form 
powder
color 
white to beige
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0272
Product name
Etifoxine hydrochloride
Purity
≥98% (HPLC)
Packaging
10mg
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0272
Product name
Etifoxine hydrochloride
Purity
≥98% (HPLC)
Packaging
50mg
Price
$631
Updated
2024/03/01
Tocris
Product number
3113
Product name
Etifoxine hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$757
Updated
2021/12/16
Tocris
Product number
3113
Product name
Etifoxine hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$182
Updated
2021/12/16
Usbiological
Product number
255270
Product name
Etifoxine hydrochloride
Packaging
10mg
Price
$423
Updated
2021/12/16
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6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Chemical Properties,Usage,Production

Chemical Properties

Low Melting White Solid

Uses

Psychotropic agent with anxiolytic and anticonvulsant activity.

Uses

Etifoxine hydrochloride has been used as a γ-aminobutyric acid (GABA)-receptor agonist to study its effects on insulin expression in α cell line (αTC1)

Biochem/physiol Actions

Etifoxine is an anxiolytic anticonvulsant, which promotes axonal regeneration. It binds to β2 and β3 subunits of the GABAA receptor complex, a different target site to benzodiazepines, and binds to the translocator protein (18 kDa) TSPO, formerly known as the peripheral or mitochondrial benzodiazepine receptor. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. Whereas, its anxiolytic effects involve GABAA receptors and TSPO, etifoxine′s neuroregenerative effects mainly involve TSPO.

storage

Store at +4°C

6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Etifoxine Hydrochloride 56776-32-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

56776-32-0, 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochlorideRelated Search:


  • 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride
  • Etifoxine·hydrochloride
  • 6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminehydrochloride
  • 2-EthylaMino-6-chloro-4-Methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride
  • 6-Chloro-N-ethyl-4-Methyl-4-phenyl-4H-3,1-benzoxazin-2-aMine Hydrochloride
  • StresaM
  • 6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride
  • HOE-36801 hydrochloride
  • NSC 163501;ANTIBIOTIC AT-125;U 42126
  • Etifoxine HCl
  • TBPS,Anxiolytic,Etifoxine hydrochloride,γ-Aminobutyric acid Receptor,disorder,HOE 36-801,inhibit,adjustment,Etifoxine,Inhibitor,Gamma-aminobutyric acid Receptor,GABA Receptor
  • Etifoxine HCl (HOE-36801)
  • 56776-32-0
  • C17H17ClN2OHCl
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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