7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone

Product Name: 7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
CAS No.: 34564-13-1
Chemical Name: 7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
Synonyms: EMI48;3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)coumarin;7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone;7-Diethylamino-3-(5-methylbenzoxazol-2-yl)-2H-1-benzopyran-2-one;3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(5-methyl-2-benzoxazolyl)-
CBNumber: CB3892130
Molecular Formula: C21H20N2O3
Formula Weight: 348.4
MOL File: 34564-13-1.mol

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7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone Property

storage temp.: Store at -20°C
solubility: DMSO: 9.26 mg/mL (26.58 mM)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0128109
Product name: EMI48
Purity: 99.02%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0128109
Product name: EMI48
Purity: 99.02%
Packaging: 10mg
Price: $480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0003390
Product name: 7-(DIETHYLAMINO)-3-(5-METHYLBENZOXAZOL-2-YL)-2-BENZOPYRONE
Purity: 95.00%
Packaging: 5MG
Price: $504.74
Updated: 2021/12/16

ChemScene

Product number: CS-0128109
Product name: EMI48
Purity: 99.02%
Packaging: 50mg
Price: $1400
Updated: 2021/12/16

ChemScene

Product number: CS-0128109
Product name: EMI48
Purity: 99.02%
Packaging: 100mg
Price: $2000
Updated: 2021/12/16

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7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone Chemical Properties,Usage,Production

Uses

EMI48, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI48 inhibits EGFR triple mutants[1].

IC 50

EGFR^{L858R/T790M/C797S}; EGFR^{del19 T790M C797S}

storage

Store at -20°C

References

[1] Punit Saraon , et al. A Drug Discovery Platform to Identify Compounds That Inhibit EGFR Triple Mutants.Nat Chem Biol. 2020 May;16(5):577-586. DOI:10.1038/s41589-020-0484-2

7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone Preparation Products And Raw materials

Raw materials

Preparation Products

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7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone Suppliers

China 8 United States 2 Global 10

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34564-13-1, 7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyroneRelated Search:

7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone (E)-5-Methyl-2-styrylbenzoxazole BENZOOXAZOL-2-YL-ACETIC ACID 3-(benzoxazol-2-yl)-7-(diethylamino)-2-benzopyrone

7-(diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone

3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one

3-(5-Methylbenzoxazole-2-yl)-7-(diethylamino)coumarin

7-Diethylamino-3-(5-methylbenzoxazol-2-yl)-2H-1-benzopyran-2-one

EMI48

2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(5-methyl-2-benzoxazolyl)-

34564-13-1