debrisoquine
- Product Name
- debrisoquine
- CAS No.
- 1131-64-2
- Chemical Name
- debrisoquine
- Synonyms
- ebrisoquin;Debrisochin;Debrisoquin;debrisoquine;Isocaramidine;Debrisoquine Monomer;3,4-Dihydro-2(1H)-isoquinolinecarbimidamide;3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXAMIDINE;3,4-dihydro-1H-isoquinoline-2-carboximidamide;3,4-Dihydro-2(1H)-isoquinolinecarboximidamide
- CBNumber
- CB3904530
- Molecular Formula
- C10H13N3
- Formula Weight
- 175.23
- MOL File
- 1131-64-2.mol
debrisoquine Property
- Melting point:
- 278-280 °C
- Boiling point:
- 309.8±52.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- pka
- pKa 11.9 (Uncertain)
N-Bromosuccinimide Price
- Product number
- D1814
- Product name
- Debrisoquin
- Packaging
- 100mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- B426748
- Product name
- 3,4-Dihydroisoquinoline-2(1H)-carboximidamide
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- API0000508
- Product name
- DEBRISOQUINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $188.1
- Updated
- 2021/12/16
- Product number
- API0000508
- Product name
- DEBRISOQUINE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $697.34
- Updated
- 2021/12/16
- Product number
- R2688
- Product name
- 3,4-dihydro-2(1H)-Isoquinolinecarboximidamide
- Purity
- 97.00%
- Packaging
- 1G
- Price
- $1940
- Updated
- 2021/12/16
debrisoquine Chemical Properties,Usage,Production
Originator
Declinax,Roche,UK,1967
Uses
Antihypertensive.
Definition
ChEBI: Debrisoquin is a member of isoquinolines and a carboxamidine. It has a role as an antihypertensive agent, an adrenergic agent, a sympatholytic agent and a human metabolite.
Manufacturing Process
27 g of 1,2,3,4-tetrahydroisoquinoline was added at room temperature to a
solution of 28 g of 2-methyl-2-isothiourea sulfate in 80 ml of water. The
resulting mixture was kept at room temperature with occasional shaking. After
a short period of time, methylmercaptan began to escape, and the mixture
warmed up slightly. After then standing for 24 hours, crystals formed. They
were filtered off and rinsed with ice cold water. Recrystallization from
approximately 100 ml of water yielded 1,2,3,4-tetrahydroisoquinoline-2-
carboxamidine sulfate melting at 278°C to 280°C (uncorr.).
Another batch prepared in the same manner melted at 284°C to 285°C due to
a minute difference in moisture content.
Both batches prepared above analyzed correctly for (C10H13N3)2·H2SO4.
brand name
Declinax (HoffmannLaRoche).
Therapeutic Function
Antihypertensive
debrisoquine Preparation Products And Raw materials
Raw materials
Preparation Products
debrisoquine Suppliers
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