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debrisoquine

Product Name
debrisoquine
CAS No.
1131-64-2
Chemical Name
debrisoquine
Synonyms
ebrisoquin;Debrisochin;Debrisoquin;debrisoquine;Isocaramidine;Debrisoquine Monomer;3,4-Dihydro-2(1H)-isoquinolinecarbimidamide;3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXAMIDINE;3,4-dihydro-1H-isoquinoline-2-carboximidamide;3,4-Dihydro-2(1H)-isoquinolinecarboximidamide
CBNumber
CB3904530
Molecular Formula
C10H13N3
Formula Weight
175.23
MOL File
1131-64-2.mol
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debrisoquine Property

Melting point:
278-280 °C
Boiling point:
309.8±52.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
pka
pKa 11.9 (Uncertain)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
D1814
Product name
Debrisoquin
Packaging
100mg
Price
$425
Updated
2021/12/16
TRC
Product number
B426748
Product name
3,4-Dihydroisoquinoline-2(1H)-carboximidamide
Packaging
10mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000508
Product name
DEBRISOQUINE
Purity
95.00%
Packaging
5MG
Price
$188.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000508
Product name
DEBRISOQUINE
Purity
95.00%
Packaging
100MG
Price
$697.34
Updated
2021/12/16
AccelPharmtech
Product number
R2688
Product name
3,4-dihydro-2(1H)-Isoquinolinecarboximidamide
Purity
97.00%
Packaging
1G
Price
$1940
Updated
2021/12/16
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debrisoquine Chemical Properties,Usage,Production

Originator

Declinax,Roche,UK,1967

Uses

Antihypertensive.

Definition

ChEBI: Debrisoquin is a member of isoquinolines and a carboxamidine. It has a role as an antihypertensive agent, an adrenergic agent, a sympatholytic agent and a human metabolite.

Manufacturing Process

27 g of 1,2,3,4-tetrahydroisoquinoline was added at room temperature to a solution of 28 g of 2-methyl-2-isothiourea sulfate in 80 ml of water. The resulting mixture was kept at room temperature with occasional shaking. After a short period of time, methylmercaptan began to escape, and the mixture warmed up slightly. After then standing for 24 hours, crystals formed. They were filtered off and rinsed with ice cold water. Recrystallization from approximately 100 ml of water yielded 1,2,3,4-tetrahydroisoquinoline-2- carboxamidine sulfate melting at 278°C to 280°C (uncorr.).
Another batch prepared in the same manner melted at 284°C to 285°C due to a minute difference in moisture content.
Both batches prepared above analyzed correctly for (C10H13N3)2·H2SO4.

brand name

Declinax (HoffmannLaRoche).

Therapeutic Function

Antihypertensive

debrisoquine Preparation Products And Raw materials

Raw materials

Preparation Products

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debrisoquine Suppliers

Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@qq.com
Country
China
ProdList
8369
Advantage
55
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81148696 +86-15536356810
Email
1022@dideu.com
Country
China
ProdList
3882
Advantage
58
Hubei Xinyang Medical Technology Co., Ltd
Tel
15347293736 15347293736
Fax
QQ:2853117752
Email
2853117764@qq.com
Country
China
ProdList
8327
Advantage
58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd
Tel
027-59308705 18871579363
Fax
027-59308705
Email
1248180077@qq.com
Country
China
ProdList
9950
Advantage
58
Hebei Zhenjia new material Co., LTD
Tel
0319-5925599 13315915972
Email
13313090628@163.com
Country
China
ProdList
2918
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
Country
China
ProdList
9982
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
Advantage
58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
Tel
18502726233; 18502726233
Email
3641133981@qq.com
Country
China
ProdList
9705
Advantage
58
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View Lastest Price from debrisoquine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
debrisoquine 1131-64-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
5000KG
Release date
2024-07-18