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sulforidazine

Product Name
sulforidazine
CAS No.
14759-06-9
Chemical Name
sulforidazine
Synonyms
sulforidazine;Thioridazine 2-Sulfone;Thioridazine EP Impurity E;Thioridazine Impurity 5 (Thioridazine EP Impurity E);10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-;10-[2-[(2RS)-1-Methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine;10-[2-[(2RS)-1-methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine (sulforidazine);10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine (Thioridazine Impurity)
CBNumber
CB3920154
Molecular Formula
C21H26N2O2S2
Formula Weight
402.57
MOL File
14759-06-9.mol
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sulforidazine Property

Melting point:
121-123°
Boiling point:
589.1±50.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, Under Inert Atmosphere
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
9.83±0.10(Predicted)
color 
Off-White to Dark Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T368810
Product name
Thioridazine2-Sulfone
Packaging
50mg
Price
$1455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012528
Product name
SULFORIDAZINE
Purity
95.00%
Packaging
5MG
Price
$345.4
Updated
2021/12/16
aablocks
Product number
AA001EXB
Product name
10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
Packaging
5mg
Price
$315
Updated
2021/12/16
aablocks
Product number
AA001EXB
Product name
10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
Packaging
50mg
Price
$1470
Updated
2021/12/16
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sulforidazine Chemical Properties,Usage,Production

Chemical Properties

Thick Yellow Oil

Originator

Sulforidazine,ZYF Pharm Chemical

Uses

Thioridazine 2-Sulfone (Thioridazine EP Impurity E) is a major metabolite of Thioridazine (THD 2-SO2).

Definition

ChEBI: Sulforidazine is a member of phenothiazines.

Manufacturing Process

A mixture of 96.5 g 2-methylsulfonylphenothiazine, 50 g 2-(2-chloroethyl)-1- methylpiperidine, 62 g diethyl carbonate and 2 g sodium methylate was heated at 135°C for 1 hour and then at 180-190°C for 2.5 hours. The product was dissolved in benzene (500 ml) and the solution was extracted with 700 ml of 15% aqueous solution tartaric acid. The extract was washed with benzene. After addition of sodium carbonate solution to the extract was obtained a precipitate which was dissolved in benzene. This solution was washed with water and concentrated. 2-Methylsulfonyl-10-(2-(1-methyl-2- piperidyl)ethyl)phenothiazin was recrystallized from acetone, melting point 121-123°C.

Therapeutic Function

Neuroleptic

sulforidazine Preparation Products And Raw materials

Raw materials

Preparation Products

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sulforidazine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94658
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76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18021
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56
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226
Email
sales@rrkchem.com
Country
China
ProdList
56086
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28180
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8864
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44843
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58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31130
Advantage
58
Zhuhai Anzhe Biotechnology Co,Ltd.
Tel
13169972583
Email
513211116@qq.com
Country
China
ProdList
3015
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-87576359 15353716720
Email
1039@dideu.com
Country
China
ProdList
10011
Advantage
58

14759-06-9, sulforidazine Related Search:


  • sulforidazine
  • Thioridazine 2-Sulfone
  • Thioridazine EP Impurity E
  • 10-[2-[(2RS)-1-Methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine
  • 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
  • Thioridazine Impurity 5 (Thioridazine EP Impurity E)
  • 10-[2-[(2RS)-1-methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine (sulforidazine)
  • 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine (Thioridazine Impurity)
  • 14759-06-9
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds