ChemicalBook > CAS DataBase List > 4-(3-Chloro-phenyl)-thiazol-2-ylamine

4-(3-Chloro-phenyl)-thiazol-2-ylamine

Product Name
4-(3-Chloro-phenyl)-thiazol-2-ylamine
CAS No.
90533-23-6
Chemical Name
4-(3-Chloro-phenyl)-thiazol-2-ylamine
Synonyms
4-(3-Chlorophenyl)-2-thiazolamine;4-(3-Chlorophenyl)thiazol-2-amine;2-Thiazolamine, 4-(3-chlorophenyl)-;4-(3-chlorophenyl)thiazol-2(3H)-imine;1-(3-chloro-5-fluorophenyl)-3-buten-1-ol
CBNumber
CB3947331
Molecular Formula
C9H7ClN2S
Formula Weight
210.68
MOL File
90533-23-6.mol
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4-(3-Chloro-phenyl)-thiazol-2-ylamine Property

Melting point:
112 °C(Solv: ethanol (64-17-5))
Boiling point:
394.2±17.0 °C(Predicted)
Density 
1.389±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
3.94±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C350830
Product name
4-(3-Chlorophenyl)thiazol-2-amine
Packaging
100mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
X6236
Product name
2-Amino-4-(3-chlorophenyl)thiazole
Packaging
100mg
Price
$83
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0022144
Product name
4-(3-CHLORO-PHENYL)-THIAZOL-2-YLAMINE
Purity
95.00%
Packaging
1G
Price
$794.34
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0022144
Product name
4-(3-CHLORO-PHENYL)-THIAZOL-2-YLAMINE
Purity
95.00%
Packaging
2.5G
Price
$1119.71
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0022144
Product name
4-(3-CHLORO-PHENYL)-THIAZOL-2-YLAMINE
Purity
95.00%
Packaging
5G
Price
$1379.44
Updated
2021/12/16
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4-(3-Chloro-phenyl)-thiazol-2-ylamine Chemical Properties,Usage,Production

Synthesis

17356-08-0

99-02-5

90533-23-6

The reaction mixture was stirred at 100 °C for 8 hours with thiourea (50 mmol), 3-chloroacetophenone (25 mmol) and iodine (25 mmol). After completion of the reaction, the mixture was cooled and extracted with ether to remove unreacted 3-chloroacetophenone. Subsequently, it was washed with aqueous sodium thiosulfate to remove excess iodine and then with cold water. The crude product was dissolved in hot water and filtered to remove the sulfone by-product. The filtrate was alkalized with aqueous Na2CO3 to afford 2-amino-4-(3-chlorophenyl)-1,3-thiazole. Finally, the crude product was purified by recrystallization from alcohol.

References

[1] Chemical and Pharmaceutical Bulletin, 2007, vol. 55, # 7, p. 1014 - 1017
[2] European Journal of Medicinal Chemistry, 2013, vol. 66, p. 305 - 313
[3] Arzneimittel-Forschung/Drug Research, 1986, vol. 36, # 9, p. 1391 - 1393
[4] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 2, p. 692 - 702
[5] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 23, p. 5428 - 5431

4-(3-Chloro-phenyl)-thiazol-2-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(3-Chloro-phenyl)-thiazol-2-ylamine Suppliers

China 50 Europe 2 Germany 1 India 3 United Kingdom 1 United States 5 Global 62
ecochem international chemical broker
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Email
export@ecochem.dk
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Europe
ProdList
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kemikalieimport
Tel
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Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
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90533-23-6, 4-(3-Chloro-phenyl)-thiazol-2-ylamine Related Search:

(4-(3,4-DICHLOROPHENYL)(2,5-THIAZOLYL))-3-PYRIDYLAMINE 5-BROMO-2-(4-BROMO-3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4-(3,4-DICHLOROPHENYL)-1,3-THIAZOLE 4-(3,4-DICHLOROPHENYL)-2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-1,3-THIAZOLE 4-(5-CHLORO-2-METHOXY-PHENYL)-THIAZOL-2-YLAMINE 4-(3,4-DICHLOROPHENYL)-1,3-THIAZOLE-2-YLAMINE, HYDROBROMIDE 2-CHLORO-N-[4-(3,4-DICHLORO-PHENYL)-THIAZOL-2-YL]-ACETAMIDE 4-(3-CHLORO-4-METHYLPHENYL)-5-METHYL-1,3-THIAZOL-2-AMINE N1-[4-(3-CHLORO-4-METHYLPHENYL)-5-METHYL-1,3-THIAZOL-2-YL]-2-CHLOROACETAMIDE 4-(3-Chloro-phenyl)-thiazol-2-ylamine N-(4-(3,4-DICHLOROPHENYL)(2,5-THIAZOLYL))-3-PYRIDYLFORMAMIDE 4-(3,4-DICHLORO-PHENYL)-THIAZOL-2-YLAMINE 4-(3-CHLORO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE (4-(3,4-DICHLOROPHENYL)(2,5-THIAZOLYL))PROP-2-ENYLAMINE AURORA KA-7859 4-(3,5-DICHLORO-2-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE SALOR-INT L124354-1EA

  • 4-(3-Chlorophenyl)thiazol-2-amine
  • 1-(3-chloro-5-fluorophenyl)-3-buten-1-ol
  • 4-(3-Chlorophenyl)-2-thiazolamine
  • 2-Thiazolamine, 4-(3-chlorophenyl)-
  • 4-(3-chlorophenyl)thiazol-2(3H)-imine
  • 90533-23-6