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Caffeine Citrate

Product Name
Caffeine Citrate
CAS No.
93390-81-9
Chemical Name
Caffeine Citrate
Synonyms
XWLUWCNOOVRFPX-UHFFFAOYSA-N;2,4-Imidazolidinedione, 5,5-diphenyl-3-[(phosphonooxy)methyl]-
CBNumber
CB3947346
Molecular Formula
C16H15N2O6P
Formula Weight
362.27
MOL File
93390-81-9.mol
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Caffeine Citrate Property

Melting point:
173-176.5°
Density 
1.495±0.06 g/cm3(Predicted)
pka
1.74±0.10(Predicted)
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Safety

Hazardous Substances Data
93390-81-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

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Caffeine Citrate Chemical Properties,Usage,Production

Description

Cerebyx was launched for the treatment of status epilepticus and for neurosurgery derived seizures. Fosphenytoin is rapidly converted by phosphatases to phenytoin. This compound is readily water soluble thus overcoming an important problem associated with Dilantin.

Originator

Warner-Lambert (USA)

Uses

Anticonvulsant.

Definition

ChEBI: Fosphenytoin is an imidazolidine-2,4-dione.

Manufacturing Process

By action of formaldehyde and hydrochloric acid on 5,5-diphenylhydantoin was prepared 3-hydroxymethyl-5,5-diphenyl-imidazolidine-2,4-dione which was converted by action PCl3 to 3-chloromethyl-5,5-diphenyl-imidazolidine-2,4- dione by action PCl3. Then the chlorine atom was substituted on P(O)(OBz)Ogroup by action of argentum salt of phosphoric acid dibenzyl ester. Removal of the protecting groups by hydrogenolysis gives the 2,4-imidazolidinedione, 5,5- diphenyl-3-((phosphonooxy)methyl)- (fosphenytoin).
In practice it is usually used as sodium salt.

brand name

Cerebyx (Parke-Davis).

Therapeutic Function

Antiepileptic, Anticonvulsant

Caffeine Citrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Caffeine Citrate Suppliers

Dayang Chem (Hangzhou) Co.,Ltd.
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571-88938639 +8617705817739
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info@dycnchem.com
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China
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Changzhou Xianglong Pharmaceutical Technology Co., LTD
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18661161657
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yaoxiangqiu2021@163.com
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China
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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China
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TargetMol Chemicals Inc.
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15002134094
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marketing@targetmol.cn
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China
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19704
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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+86-057181025280; +8617767106207
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0571-85806285
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sales@molcore.com
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