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5-Bromo-2-(dimethylamino)pyridine

Product Name
5-Bromo-2-(dimethylamino)pyridine
CAS No.
26163-07-5
Chemical Name
5-Bromo-2-(dimethylamino)pyridine
Synonyms
3-Bromo-6-dimethylaminopyridine;5-Bromo-N,N-dimethylpyridin-2-amine;5-Bromo-N,N-dimethyl-2-pyridinamine;(5-bromo-pyridin-2-yl)-dimethylamine;5-bromo-2-(N,N-dimethyl-1-yl)pyridine;2-PyridinaMine, 5-broMo-N,N-diMethyl-;5-Bromo-N,N-dimethylpyridin-2-ylamine;5-Bromo-2-(dimethylamino)pyridine ISO 9001：2015 REACH
CBNumber
CB3957798
Molecular Formula
C7H9BrN2
Formula Weight
201.06
MOL File
26163-07-5.mol
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5-Bromo-2-(dimethylamino)pyridine Property

Melting point:
69-71 °C
Boiling point:
253.5±20.0 °C(Predicted)
Density 
1.469±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
solid
pka
5.31±0.10(Predicted)
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C7H9BrN2/c1-10(2)7-4-3-6(8)5-9-7/h3-5H,1-2H3
InChIKey
XIMCGXXYEMOWQP-UHFFFAOYSA-N
SMILES
C1(N(C)C)=NC=C(Br)C=C1
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
Hazard Note 
Irritant
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00280
Product name
5-Bromo-2-dimethylaminopyridine
Packaging
1g
Price
$87.5
Updated
2025/07/31
TRC
Product number
B691533
Product name
5-Bromo-2-(dimethylamino)pyridine
Packaging
1g
Price
$75
Updated
2021/12/16
TRC
Product number
B691533
Product name
5-Bromo-2-(dimethylamino)pyridine
Packaging
250mg
Price
$55
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-Y9
Product name
5-Bromo-2-(dimethylamino)pyridine
Packaging
5G
Price
$66
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B1391
Product name
5-Bromo-2-(dimethylamino)pyridine
Purity
97%
Packaging
25g
Price
$70
Updated
2021/12/16
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5-Bromo-2-(dimethylamino)pyridine Chemical Properties,Usage,Production

Synthesis

1072-97-5

74-88-4

26163-07-5

Step 64a: Synthesis of 5-bromo-N,N-dimethylpyridin-2-amine (Compound 0601-114) To a solution of 5-bromopyridin-2-amine (1.0 g, 5.8 mmol) in tetrahydrofuran (THF, 25 mL) was added sodium hydride (NaH, 60% dispersed in mineral oil, 0.92 g, 23.1 mmol) at 0°C and the reaction mixture was stirred for 10 minutes. Subsequently, iodomethane (CH3I, 1 mL, 16 mmol) was added and the reaction continued to be stirred for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (30 mL) and extracted with ethyl acetate (3 x 30 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, 10% v/v) to give the title compound (1.1 g, 94% yield) as a white solid. LCMS: 203 [M+2]+. 1H NMR (400 MHz, DMSO-d6) δ 2.99 (s, 6H), 6.61 (d, J = 9.6 Hz, 1H), 7.62 (dd, J = 9.2, 2.8 Hz, 1H), 8.12 (d, J = 2.4 Hz, 1H).

References

[1] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 206
[2] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0485; 0486
[3] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0418

5-Bromo-2-(dimethylamino)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-(dimethylamino)pyridine Suppliers

China 93 Germany 1 India 1 United Kingdom 4 United States 8 Global 107
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
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View Lastest Price from 5-Bromo-2-(dimethylamino)pyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-Bromo-2-(dimethylamino)pyridine 26163-07-5
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Bromo-2-(dimethylamino)pyridine 26163-07-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Bromo-2-(dimethylamino)pyridine 26163-07-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

26163-07-5, 5-Bromo-2-(dimethylamino)pyridineRelated Search:

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  • 2-PyridinaMine, 5-broMo-N,N-diMethyl-
  • 5-Bromo-N,N-dimethyl-2-pyridinamine
  • 5-Bromo-N,N-dimethylpyridin-2-amine
  • 5-bromo-2-(N,N-dimethyl-1-yl)pyridine
  • (5-bromo-pyridin-2-yl)-dimethylamine
  • 3-Bromo-6-dimethylaminopyridine
  • 5-Bromo-2-(dimethylamino)pyridine ISO 9001：2015 REACH
  • 5-Bromo-N,N-dimethylpyridin-2-ylamine
  • 26163-07-5
  • alkyl bromide
  • Pyridine
  • Amino
  • Organohalides