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3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE

Product Name
3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE
CAS No.
1666-04-2
Chemical Name
3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE
Synonyms
3,6-Dimethylsalicylaldehyde;3,6-Dimethylsalicylaldehyde>3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE;Benzaldehyde, 2-hydroxy-3,6-dimethyl-;3,6-Dimethyl-2-formylphenol, 2-Formyl-3-hydroxy-p-xylene, 3,6-Dimethylsalicylaldehyde
CBNumber
CB41010273
Molecular Formula
C9H10O2
Formula Weight
150.17
MOL File
1666-04-2.mol
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3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE Property

Melting point:
59.0 to 63.0 °C
Boiling point:
230.1±35.0 °C(Predicted)
Density 
1.136±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
soluble in Methanol
form 
powder to crystal
pka
8.63±0.15(Predicted)
color 
White to Light yellow to Light orange
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Safety

HS Code 
2912490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4507
Product name
3,6-Dimethylsalicylaldehyde
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$180
Updated
2025/07/31
TCI Chemical
Product number
D4507
Product name
3,6-Dimethylsalicylaldehyde
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$599
Updated
2025/07/31
TRC
Product number
H824985
Product name
2-Hydroxy-3,6-dimethylbenzaldehyde
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
H824985
Product name
2-Hydroxy-3,6-dimethylbenzaldehyde
Packaging
250mg
Price
$70
Updated
2021/12/16
TRC
Product number
H824985
Product name
2-Hydroxy-3,6-dimethylbenzaldehyde
Packaging
500mg
Price
$105
Updated
2021/12/16
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3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE Chemical Properties,Usage,Production

Uses

2-Hydroxy-3,6-dimethylbenzaldehyde

Synthesis

95-87-4

50-00-0

1666-04-2

To a solution of 2,5-dimethylphenol (7.0 g, 57.3 mmol) in acetonitrile (250 mL) was sequentially added triethylamine (30.1 mL, 0.212 mol) and magnesium chloride (8.17 g, 86 mmol). The reaction mixture was stirred at room temperature for 15 minutes before adding paraformaldehyde (11.5 g, 0.38 mol). Subsequently, the mixture was heated to 80 °C and kept for 20 hours. After completion of the reaction, acetonitrile was removed by distillation under reduced pressure. A 10% hydrochloric acid solution was added to the residue and stirred for 30 min at room temperature. The mixture was extracted with dichloromethane (2 x 40 mL), the organic layers were combined and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure and the resulting crude product was purified by fast column chromatography on silica gel (eluent: dichloromethane) to afford the target product 3,6-dimethyl-2-hydroxybenzaldehyde (27a) (3.56 g, 23.7 mmol, 42% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 2.21 (s, 3H), 2.57 (s, 3H), 6.62 (d, J = 8.0 Hz, 1H), 7.24 (d, J = 8.0 Hz, 1H), 10.30 (s, 1H), 12.18 (s, 1H).

References

[1] Journal of Organometallic Chemistry, 2005, vol. 690, # 23, p. 5125 - 5144
[2] Journal of the Chemical Society, Perkin Transactions 2, 2001, # 9, p. 1573 - 1584
[3] Patent: WO2012/140243, 2012, A1. Location in patent: Page/Page column 137-138
[4] Journal of Organic Chemistry, 2013, vol. 78, # 14, p. 6890 - 6910
[5] Patent: US2016/152543, 2016, A1. Location in patent: Paragraph 1197; 1198; 1199

3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE Suppliers

Americas 1 China 67 Europe 2 India 4 Japan 1 United Kingdom 1 United States 8 Global 84
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
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58
CHEMSWORTH
Tel
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Fax
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Email
info@chemsworth.com
Country
India
ProdList
6700
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A.J Chemicals
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Email
sales@ajchem.in
Country
India
ProdList
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View Lastest Price from 3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
2-Hydroxy-3,6-dimethylbenzaldehyde 1666-04-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-10-23
Career Henan Chemical Co
Product
3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE 1666-04-2
Price
US $3.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
200KG
Release date
2020-01-07

1666-04-2, 3,6-DIMETHYL-2-HYDROXY BENZALDEHYDERelated Search:

FUMARPROTOCETRARIC ACID 2-HYDROXY-3-ISOPROPYL-6-METHYLBENZOIC ACID LASALOCID A SODIUM SALT Mycophenolic acid ATRANORIN 2-HYDROXY-6-ISOPROPYL-3-METHYLBENZOIC ACID PSOROMIC ACID OCHRATOXIN A Adriamycin TOLUALDEHYDES ISLANDICIN STICTIC ACID CYNODONTIN 3-tert-butyl-2-hydroxy-6-methylbenzoic acid CATENARIN 1,4-DIHYDROXY-2,3-DIMETHYLANTHRAQUINONE AMMONIUM CARMINATE VINEOMYCINE A1

  • 3,6-DIMETHYL-2-HYDROXY BENZALDEHYDE
  • 3,6-Dimethyl-2-formylphenol, 2-Formyl-3-hydroxy-p-xylene, 3,6-Dimethylsalicylaldehyde
  • 3,6-Dimethylsalicylaldehyde
  • 3,6-Dimethylsalicylaldehyde&gt
  • Benzaldehyde, 2-hydroxy-3,6-dimethyl-
  • 1666-04-2