L-Tyrosinol hydrochloride
- Product Name
- L-Tyrosinol hydrochloride
- CAS No.
- 87745-27-5
- Chemical Name
- L-Tyrosinol hydrochloride
- Synonyms
- H-Tyr-ol;L-Tyr-ol;L-TYROSINOL;H-Tyrosinol;H-Tyrosinol·HCl;L-Tyrosinol hydrochloride;L-TYROSINOL HYDROCHLORIDE 98%;L-Tyrosinol hydrochloride,97%;
L -Tyrosinol hydrochloride;L-Tyrosinol hydrochloride USP/EP/BP - CBNumber
- CB4102591
- Molecular Formula
- C9H14ClNO2
- Formula Weight
- 203.67
- MOL File
- 87745-27-5.mol
L-Tyrosinol hydrochloride Property
- Melting point:
- 161-165 °C(lit.)
- alpha
- -19 º (C=1, H2O 22 ºC)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- Appearance
- White to off-white Solid
- optical activity
- [α]22/D 18°, c = 1 in H2O
- CAS DataBase Reference
- 87745-27-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 469998
- Product name
- L-Tyrosinol hydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $60.84
- Updated
- 2025/07/31
- Product number
- S193
- Product name
- L-Tyrosinol hydrochloride
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 202014
- Product name
- L-Tyrosinol
- Purity
- >=98%
- Packaging
- 5g
- Price
- $352
- Updated
- 2021/12/16
- Product number
- AAA0001516
- Product name
- L-TYROSINOL HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $625
- Updated
- 2021/12/16
- Product number
- AAA0001516
- Product name
- L-TYROSINOL HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1065.66
- Updated
- 2021/12/16
L-Tyrosinol hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to beige granular powder
Uses
peptide synthesis
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
3417-91-2
87745-27-5
10125-12-9
General procedure for the synthesis of L-tyrosinol hydrochloride and compounds (CAS:10125-12-9) from L-tyrosine methyl ester hydrochloride: the reaction was carried out in a 0.5 L stainless steel autoclave with stirring at 500 rpm to assess the activity of the catalyst for the hydrogenation of R-phenylglycine methyl ester. First, 1 g of catalyst (20-40 mesh) was loaded into the reactor and subsequently purged five times with H2 to remove air. The catalyst was reduced at 1 MPa H2 pressure and 250 °C for 4 hours. After the autoclave was cooled to room temperature in H2 atmosphere, 1.5 g of R-phenylglycine methyl ester (R-p-m) diluted by 150 mL of ethanol (R-p-m/Cat = 1.5, w/w) was added. The standard reaction conditions were set at 5 MPa H2 pressure and 80 °C temperature for 10 h. The reaction was carried out in an autoclave. Upon completion of the reaction, the autoclave was cooled to room temperature in H2 atmosphere. Subsequently, the solid catalyst was separated by centrifugation. The product was purified by silica gel column chromatography using ethyl acetate/methanol (3/2, v/v) as eluent. Finally, the light yellow powdery product was obtained by rotary evaporation. The analysis of the reactants and products was carried out using a high performance liquid chromatograph (HPLC, Agilent 1260 Infinity) equipped with a UV detector and an Eclipse XDB-C18 column (150 × 4.6 mm, 5 μm particles), which in turn was used to calculate the conversion of R-phenylglycine methyl ester (X), yield (Y), and chemoselectivity for R-phenylglycine (S), where yield is the liquid chromatographic yield. The enantiomeric excess values (ee values) of the products were determined by HPLC equipped with a UV detector (wavelength 258 nm) and a chiral column (CHIRALPAK AY-H, 250 × 4.6 mm, 5 μm particle size).
References
[1] Catalysis Letters, 2017, vol. 147, # 8, p. 2160 - 2166
L-Tyrosinol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
L-Tyrosinol hydrochloride Suppliers
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
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View Lastest Price from L-Tyrosinol hydrochloride manufacturers
- Product
- L-Tyrosinol hydrochloride 87745-27-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2025-03-10
- Product
- L-Tyr-OL.Hcl 87745-27-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-01-17