Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)

Product Name: Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.: 146552-71-8
Chemical Name: Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms: (S)-N2-Boc-1,2-propanediamine;(S)-2-N-Boc-propane-1,2-diaMine;(S)-tert-butyl 1-aminopropan-2-ylcarbamate;tert-Butyl ((S)-1-aminopropan-2-yl)carbamate;tert-butyl N-[(2S)-1-aMinopropan-2-yl]carbaMate;tert-butyl N-[(1S)-2-amino-1-methyl-ethyl]carbamate;((S)-2-Amino-1-methyl-ethyl)-carbamic acid tert-butyl ester;N-((S)-2-Amino-1-methylethyl)carbamic acid tert-butyl ester;N-[(1S)-2-Amino-1-methylethyl]-carbamic acid tert-butyl ester;Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester
CBNumber: CB41064195
Molecular Formula: C8H18N2O2
Formula Weight: 174.24
MOL File: 146552-71-8.mol

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Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) Property

Boiling point:: 264℃
Density: 0.984
Flash point:: 113℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 12.19±0.46(Predicted)
Appearance: Yellow to brown Solid

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Safety

HS Code: 2924190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B943123
Product name: (S)-tert-Butyl1-Aminopropan-2-ylcarbamate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-0028277
Product name: (S)-tert-Butyl1-aminopropan-2-ylcarbamate
Purity: 97.0%
Packaging: 100mg
Price: $78
Updated: 2021/12/16

ChemScene

Product number: CS-0028277
Product name: (S)-tert-Butyl1-aminopropan-2-ylcarbamate
Purity: 97.0%
Packaging: 250mg
Price: $137
Updated: 2021/12/16

AK Scientific

Product number: CS-0028277
Product name: (S)-tert-Butyl1-aminopropan-2-ylcarbamate
Packaging: 1g
Price: $278
Updated: 2021/12/16

ChemScene

Product number: CS-0028277
Product name: (S)-tert-Butyl1-aminopropan-2-ylcarbamate
Purity: 97.0%
Packaging: 1g
Price: $286
Updated: 2021/12/16

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Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production

Synthesis

146610-69-7

146552-71-8

General procedure for the synthesis of tert-butyl (S)-(1-aminopropan-2-yl)carbamate from the compound (CAS: 146610-69-7): Pd/C (10%, 2 g) was added to a solution of tert-butyl (S)-1-azidopropan-2-ylcarbamate (75.0 g, 0.375 mol) in methanol (1 L). The suspension was stirred at room temperature under hydrogen atmosphere for 4 hours. After completion of the reaction, the reaction mixture was filtered and the solid was washed with methanol (100 mL). The combined filtrates were concentrated under vacuum to afford tert-butyl (S)-1-aminopropan-2-ylcarbamate (65.1 g, quantitative yield), which was used directly in the next step without further purification.1H NMR (300 MHz, CDCl3) δ ppm: 4.64 (br s, 1H), 3.64 (m, 1H), 2.75 (dd, J = 13.2, 5.1 Hz, 1H), 2.63 (dd, J = 13.2, 6.6 Hz, 1H), 1.45 (s, 9H), 1.31 (br s, 2H), 1.12 (d, J = 6.6 Hz, 3H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 24, p. 5743 - 5747
[2] Journal of Chemical Research, Miniprint, 1992, # 12, p. 3117 - 3132
[3] Patent: US2004/208828, 2004, A1. Location in patent: Page 13
[4] Organic Letters, 2011, vol. 13, # 13, p. 3486 - 3489
[5] Organic and Biomolecular Chemistry, 2013, vol. 11, # 17, p. 2780 - 2786

Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) Suppliers

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View Lastest Price from Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

Career Henan Chemical Co

Product: Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) 146552-71-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

146552-71-8, Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)Related Search:

S-2-N-BOC-propane-1,2-diamine-HCl (S)-[1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER R-1-N-CBZ-propane-1,2-diamine-HCl (R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester benzyl 2-aMinopropylcarbaMate (R)-benzyl 2-aMinopropylcarbaMate 1-Piperazinecarboxylic acid, 3,5-diMethyl-, 1,1-diMethylethyl ester, (3S,5S)- Carbamic acid, (2-amino-1-methylethyl)-, 1,1-dimethylethyl ester (9CI) (R)-tert-butyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan- 2-N-BOC-propane-1,2-diamine-HCl [1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER (R)-[1-(4-Bromophenyl)ethyl]carbamic acid tert-butyl ester 3,5-Dimethyl-piperazine-1-carboxylic acid tert-butyl ester (3R,5R)-1-Boc-3,5-diMethylpiperazine S-1-N-CBZ-propane-1,2-diamine-HCl S-2-N-BOC-propane-1,2-diamine hydrochloride

Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)

(S)-tert-butyl 1-aminopropan-2-ylcarbamate

tert-butyl N-[(2S)-1-aMinopropan-2-yl]carbaMate

N-((S)-2-Amino-1-methylethyl)carbamic acid tert-butyl ester

tert-Butyl ((S)-1-aminopropan-2-yl)carbamate

((S)-2-Amino-1-methyl-ethyl)-carbamic acid tert-butyl ester

(S)-N2-Boc-1,2-propanediamine

(S)-2-N-Boc-propane-1,2-diaMine

CarbaMic acid, N-[(1S)-2-aMino-1-Methylethyl]-, 1,1-diMethylethyl ester

Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester

N-[(1S)-2-Amino-1-methylethyl]-carbamic acid tert-butyl ester

tert-butyl N-[(1S)-2-amino-1-methyl-ethyl]carbamate

146552-71-8

N-BOC