(R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester

Product Name: (R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester
CAS No.: 100927-10-4
Chemical Name: (R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester
Synonyms: (R)-2-N-Boc-propane-1,2-diaMine;(R)-2-(Boc-amino)-1-propanamine;(R)-2-(Boc-aMino)-propanaMine HCl;R-2-N-BOC-propane-1,2-diamine-HCl;(R)-tert-butyl 1-aminopropan-2-ylcarbamate;tert-butyl (R)-1-aMinopropan-2-ylcarbaMate;tert-Butyl (R)-1-aMinopropan-2-ylcarbaMate HCl;tert-butyl N-[(2R)-1-aMinopropan-2-yl]carbaMate;(R)-1-Aminopropan-2-ylcarbamic Acid tert-Buty Ester;tert-butyl N-[(1R)-2-amino-1-methyl-ethyl]carbamate
CBNumber: CB71048936
Molecular Formula: C8H18N2O2
Formula Weight: 174.24
MOL File: 100927-10-4.mol

More

Less

(R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester Property

Boiling point:: 264℃
Density: 0.984
Flash point:: 113℃
storage temp.: 2-8°C(protect from light)
pka: 12.19±0.46(Predicted)
Appearance: White to off-white Solid

More

Less

Safety

HS Code: 2924190090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

TRC

Product number: A628140
Product name: (R)-1-Aminopropan-2-ylcarbamicAcidtert-ButyEster
Packaging: 1g
Price: $1320
Updated: 2021/12/16

Matrix Scientific

Product number: 176283
Product name: tert-Butyl (1R)-2-amino-1-methylethylcarbamate
Packaging: 10g
Price: $1602
Updated: 2021/12/16

Apolloscientific

Product number: OR943505
Product name: (R)-2-N-Boc-propane-1,2-diamine
Packaging: 1g
Price: $608
Updated: 2021/12/16

Matrix Scientific

Product number: 176283
Product name: tert-Butyl (1R)-2-amino-1-methylethylcarbamate
Packaging: 5g
Price: $1206
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB43420
Product name: (R)-tert-Butyl (1-aminopropan-2-yl)carbamate
Packaging: 250mg
Price: $300
Updated: 2021/12/16

More

Less

(R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester Chemical Properties,Usage,Production

Uses

(R)-1-Aminopropan-2-ylcarbamic Acid tert-Buty Ester is used as an intermediate in the preparation of potent benzothiophene inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK 2).

Synthesis

146610-69-7

100927-10-4

To a stirred solution of tert-butyl (S)-1-azidopropan-2-ylcarbamate (S2-3) (6.0 g, 30 mmol) in ethyl acetate (50.0 mL) was added 10% Pd/C (2.3 g). The reaction mixture was stirred at room temperature under hydrogen atmosphere (1 atm) for 15 hours. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the diatomaceous earth was washed with ethyl acetate. The filtrate was concentrated under reduced pressure to afford tert-butyl N-[(1R)-2-amino-1-methylethyl]carbamate (S2-4) (4.8 g, 92% yield) as a light yellow solid.1H NMR (400 MHz, DMSO-d6) δ 0.95 (d, J = 6.6 Hz, 3H), 1.36 (s, 9H), 2.49 (m, 2H), 3.32 (m, 1H), 6.49 (br s, 1H).

References

[1] Patent: US2016/75720, 2016, A1. Location in patent: Paragraph 0247

(R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester Suppliers

Canada 1 China 98 Europe 1 India 1 United Kingdom 2 United States 11 Global 114

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Chengdu HappySyn Pharmaceutical Technology Co., Ltd.

Tel: 028-85114309 18982182443
Email: yangli@happysyn.com
Country: China
ProdList: 2150
Advantage: 55

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Acesys Pharmatech

Tel: 18860950986
Email: tangmanman@zenjipharma.com
Country: China
ProdList: 1733
Advantage: 55

AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: 15928766785 15928766785
Fax: QQ961458712
Email: wupengcheng@astatech.cn
Country: China
ProdList: 1987
Advantage: 55

More

Less

View Lastest Price from (R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester manufacturers

Career Henan Chemical Co

Product: (R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty Ester 100927-10-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-31

100927-10-4, (R)-1-AMinopropan-2-ylcarbaMic Acid tert-Buty EsterRelated Search:

S-2-N-BOC-propane-1,2-diamine-HCl (S)-[1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER R-1-N-CBZ-propane-1,2-diamine-HCl benzyl 2-aMinopropylcarbaMate (R)-benzyl 2-aMinopropylcarbaMate Carbamic acid, [(1S)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI) 1-Piperazinecarboxylic acid, 3,5-diMethyl-, 1,1-diMethylethyl ester, (3S,5S)- Carbamic acid, (2-amino-1-methylethyl)-, 1,1-dimethylethyl ester (9CI) (R)-tert-butyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan- 2-N-BOC-propane-1,2-diamine-HCl [1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER (R)-[1-(4-Bromophenyl)ethyl]carbamic acid tert-butyl ester 3,5-Dimethyl-piperazine-1-carboxylic acid tert-butyl ester (3R,5R)-1-Boc-3,5-diMethylpiperazine S-1-N-CBZ-propane-1,2-diamine-HCl S-2-N-BOC-propane-1,2-diamine hydrochloride

Carbamic acid, [(1R)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester (9CI)

tert-butyl (R)-1-aMinopropan-2-ylcarbaMate

(R)-2-N-Boc-propane-1,2-diaMine

(R)-tert-butyl 1-aminopropan-2-ylcarbamate

R-2-N-BOC-propane-1,2-diamine-HCl

(R)-2-(Boc-aMino)-propanaMine HCl

tert-butyl N-[(2R)-1-aMinopropan-2-yl]carbaMate

tert-Butyl (R)-1-aMinopropan-2-ylcarbaMate HCl

tert-butyl (R)-1-aMinopropan-2-ylcarbaMate hydrochloride

N-[(1R)-2-Amino-1-methylethyl]carbamic acid tert-butyl ester

(R)-1-Aminopropan-2-ylcarbamic Acid tert-Buty Ester

(R)-2-(Boc-amino)-1-propanamine

tert-butyl N-[(1R)-2-amino-1-methyl-ethyl]carbamate

((R)-2-Amino-1-methyl-ethyl)-carbamic acid tert-butyl ester

Carbamic acid, N-[(1R)-2-amino-1-methylethyl]-, 1,1-dimethylethyl ester

1,1-Dimethylethyl N-[(1R)-2-amino-1-methylethyl]carbamate

N-[(R)-2-Amino-1-methylethyl]-carbamic acid tert-butyl ester

100927-10-4

N-BOC