ChemicalBook > CAS DataBase List > NPX809
NPX809
- Product Name
- NPX809
- CAS No.
- 1693734-80-3
- Chemical Name
- NPX809
- Synonyms
- NPX800;NPX809;NXP-800;NXP-800,Heat shock proteins,NXP 800,inhibit,NXP800,CCT-361814,HSP,Inhibitor,CCT 361814;6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-fluorophenyl]-2-[(4-ethyl-1-piperazinyl)methyl]-
- CBNumber
- CB410819294
- Molecular Formula
- C32H32FN5O4
- Formula Weight
- 569.63
- MOL File
- 1693734-80-3.mol
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NPX809 Property
- Boiling point:
- 612.2±55.0 °C(Predicted)
- Density
- 1.347±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (175.55 mM; Need ultrasonic)
- pka
- 11.46±0.70(Predicted)
- form
- Solid
- color
- Light yellow to green yellow
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NPX809 Chemical Properties,Usage,Production
Biological Activity
NXP800 (CCT361814) is a potent heat shock factor 1 (HSF1) inhibitor. NXP800 has the potential for cancer research[1]. NXP800 (example 169) inhibits U20S cells viability (IC50=0.056 μM)[1].
References
[1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.
NPX809 Preparation Products And Raw materials
Raw materials
Preparation Products
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