AMANTANIUM BROMIDE

Product Name: AMANTANIUM BROMIDE
CAS No.: 58158-77-3
Chemical Name: AMANTANIUM BROMIDE
Synonyms: Amantanil bromidum;AMANTANIUM BROMIDE;Amantanium bromide, 10 mM in DMSO;inhibit,Amantanium bromide,Amantanium,Inhibitor
CBNumber: CB41093142
Molecular Formula: C25H46BrNO2
Formula Weight: 472.54224
MOL File: 58158-77-3.mol

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AMANTANIUM BROMIDE Property

Melting point:: 182-184°
storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Safety

Toxicity: LD50 orally in mice: 910 mg/kg (Rovati)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0016737
Product name: AMANTANIUM BROMIDE
Purity: 95.00%
Packaging: 5MG
Price: $503.02
Updated: 2021/12/16

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AMANTANIUM BROMIDE Chemical Properties,Usage,Production

Description

Amantanium bromide is a quaternary ammonium antibacterial/antifugal agent useful as a surgical antiseptic and for the topical therapy of mucous and cutaneous infections. It appears somewhat more effective than cetylpyridinium chloride and benzalkonium chloride.

Originator

Rotta Research (Italy)

Manufacturing Process

A solution of 21.7 g (0.11 mole) 1-adamantanecarboxylic acid chloride in 100 ml ether was added to a solution of 19.4 g (0.22 mole) 2- dimethylaminoethanol in 200 ml ether. The reaction mixture was stirred overnight at room temperature. Then additional 15.0 g (0.17 mole) 2- dimethylaminoethanol was added and the reaction mixture again stirred overnight. The reaction mixture was poured into 300 ml water and treated with 20 ml of 10% NaOH solution. From the ether layer was recovered 23.0 g of 2-dimethylaminoethyl 1-adamantanecarboxylate as oil.
The 2-dimethylaminoethyl 1-adamantanecarboxylate was mixed with 1- bromodecan and allowed to stand for about 6 weeks. The resultant crystalline mass was washed with ether and dried to gave 2-(1’- adamantanecarbonyloxy)ethyldimethyldecylammonium bromide as white crystals, melting point 183°-184.5°C (two recrystallizations from ethyl acetate).

brand name

AMANTOL

Therapeutic Function

Antiseptic

AMANTANIUM BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMANTANIUM BROMIDE Suppliers

China 19 United States 5 Global 24

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58158-77-3, AMANTANIUM BROMIDERelated Search:

cyprodenate 1-Adamantanemethanol 1-Adamantanecarboxylic acid ADAMANTANE-1-CARBOXYLIC ACID METHYL ESTER ETHYL CYCLOHEXANEPROPIONATE Ethyl adamantane-1-carboxylate AMANTANIUM BROMIDE BUTYRYLCHOLINE BROMIDE

AMANTANIUM BROMIDE

Amantanil bromidum

inhibit,Amantanium bromide,Amantanium,Inhibitor

Amantanium bromide, 10 mM in DMSO

58158-77-3