ChemicalBook > CAS DataBase List > H-TYR-NH2 HCL

H-TYR-NH2 HCL

Product Name
H-TYR-NH2 HCL
CAS No.
4985-46-0
Chemical Name
H-TYR-NH2 HCL
Synonyms
L-Tyr-NH2;H-TYR-NH2;TYROSINE-NH2;TYROSINAMIDE;H-TYR-NH2 HCL;L-TYROSINAMIDE;L-TYROSINE AMIDE;TYROSINE-NH2 HCL;H-Tyr-NH2 Hydrochloride;H-TYR-NH2 HCL USP/EP/BP
CBNumber
CB4109459
Molecular Formula
C9H12N2O2
Formula Weight
180.2
MOL File
4985-46-0.mol
More
Less

H-TYR-NH2 HCL Property

Melting point:
153.5°C
Boiling point:
313.03°C (rough estimate)
Density 
1.1819 (rough estimate)
refractive index 
1.5373 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 10mg/mL; DMSO: 10mg/mL; PBS (pH 7.2): 10mg/mL
form 
A solid
pka
9.97±0.15(Predicted)
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3879
Product name
L-Tyrosinamide
Packaging
1g
Price
$77
Updated
2023/06/20
Sigma-Aldrich
Product number
T3879
Product name
L-Tyrosinamide
Packaging
5g
Price
$259
Updated
2023/06/20
TCI Chemical
Product number
T4036
Product name
L-Tyrosinamide
Packaging
1G
Price
$43
Updated
2025/07/31
TCI Chemical
Product number
T4036
Product name
L-Tyrosinamide
Packaging
5G
Price
$130
Updated
2025/07/31
Cayman Chemical
Product number
30453
Product name
L-Tyrosine amide
Packaging
500mg
Price
$37
Updated
2024/03/01
More
Less

H-TYR-NH2 HCL Chemical Properties,Usage,Production

Description

L-Tyrosine amide is a tyrosine derivative and chiral ligand that has been used in the in vitro selection of DNA aptamers for the development of aptamer-based biosensors.

Chemical Properties

White to off-white powder

Uses

L-Tyrosinamide is a derivative of Tyrosine, is an amino acid amide[1].

Definition

ChEBI: An amino acid amide that is L-tyrosine in which the carboxy OH group is replaced by NH2.

Synthesis

3417-91-2

4985-46-0

General procedure for the synthesis of (S)-2-amino-3-(4-hydroxyphenyl)propionamide from L-tyrosine methyl ester hydrochloride: L-tyrosine methyl ester hydrochloride (1.16 g, 5 mmol) was added to a 50 mL reaction vessel with concentrated ammonia (40 mL), and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the ammonia was removed by rotary evaporation followed by rotary drying. The crude product was washed with anhydrous ethanol (20 mL x 2) followed by water. Finally, it was purified by column chromatography (silica gel, 200-300 mesh; unfolding agent ratio of ethyl acetate:methanol:ammonia = 300:10:15) to afford L-tyrosine amide in 86% yield.

References

[1] Vianini E, et al. In vitro selection of DNA aptamers that bind L-tyrosinamide. Bioorg Med Chem. 2001 Oct;9(10):2543-8. DOI:10.1016/s0968-0896(01)00054-2

H-TYR-NH2 HCL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

H-TYR-NH2 HCL Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Senn Chemicals AG
Tel
--
Fax
--
Email
swiss@sennchem.com
Country
Switzerland
ProdList
3143
Advantage
71
More
Less

View Lastest Price from H-TYR-NH2 HCL manufacturers

Career Henan Chemical Co
Product
H-TYR-NH2 HCL 4985-46-0
Price
US $3.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
200kg
Release date
2020-03-06

4985-46-0, H-TYR-NH2 HCLRelated Search:


  • (S)-2-AMino-3-(4-hydroxyphenyl)propanaMide
  • (alphaS)-alpha-Amino-4-hydroxybenzenepropanamide
  • L-Tyr-NH2
  • L-Tyrosine amide≥ 98% (HPLC)
  • TYROSINE-NH2
  • TYROSINE-NH2 HCL
  • TYROSINAMIDE
  • H-Tyr-NH2 Hydrochloride
  • L-TYROSINAMIDE
  • L-TYROSINE AMIDE
  • L-TYROSINE AMIDE HYDROCHLORIDE
  • H-TYR-NH2
  • H-TYR-NH2 HCL
  • L-tyrosinamide free base
  • (2S)-2-amino-3-(4-hydroxyphenyl)propanamide
  • (2S)-2-amino-3-(4-hydroxyphenyl)propionamide
  • (2S)-2-azanyl-3-(4-hydroxyphenyl)propanamide
  • BenzenepropanaMide, a-aMino-4-hydroxy-, (S)-
  • Benzenepropanamide, α-amino-4-hydroxy-, (αS)-
  • H-TYR-NH2 HCL USP/EP/BP
  • 2-Amino-3-(4-hydroxyphenyl)propionamide
  • 4985-46-0
  • I - Z
  • Modified Amino Acids
  • Biochemicals and Reagents
  • BioChemical
  • Amino Acids and Peptides
  • Amino Acids
  • I - Z
  • Modified Amino Acids