15(S)-HETRE
- Product Name
- 15(S)-HETRE
- CAS No.
- 92693-02-2
- Chemical Name
- 15(S)-HETRE
- Synonyms
- 15(S)-HETRE;15(S) HETrE,15(S)HETrE;IUKXMNDGTWTNTP-OAHXIXLCSA-N;15S-HYDROXY-8Z,11Z,13E-EICOSATRIENOIC ACID;15(S)-HYDROXYEICOSA-8Z, 11Z, 13E-TRIENOIC ACID;8,11,13-Eicosatrienoic acid, 15-hydroxy-, (8Z,11Z,13E,15S)-
- CBNumber
- CB4110282
- Molecular Formula
- C20H34O3
- Formula Weight
- 322.48
- MOL File
- 92693-02-2.mol
15(S)-HETRE Property
- Boiling point:
- 487.4±40.0 °C(Predicted)
- Density
- 0.971±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
- pka
- 4.77±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- 36720
- Product name
- 15(S)-HETrE
- Purity
- ≥98%
- Packaging
- 25μg
- Price
- $79
- Updated
- 2024/03/01
- Product number
- 36720
- Product name
- 15(S)-HETrE
- Purity
- ≥98%
- Packaging
- 50μg
- Price
- $150
- Updated
- 2024/03/01
- Product number
- 36720
- Product name
- 15(S)-HETrE
- Purity
- ≥98%
- Packaging
- 100μg
- Price
- $280
- Updated
- 2024/03/01
- Product number
- 36720
- Product name
- 15(S)-HETrE
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $623
- Updated
- 2024/03/01
15(S)-HETRE Chemical Properties,Usage,Production
Description
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; ). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM.1 In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.2
References
1. Petrich, K., Ludwig, P., Kühn, H., et al. The suppression of 5-
2. Haviv, F., Ratajczyk, J.D., DeNet, R.W., et al. Structural requirements for the inhibition of 5-