1-(2-BROMOETHOXY)-4-FLUOROBENZENE

Product Name: 1-(2-BROMOETHOXY)-4-FLUOROBENZENE
CAS No.: 332-48-9
Chemical Name: 1-(2-BROMOETHOXY)-4-FLUOROBENZENE
Synonyms: AKOS BC-2656;ASISCHEM Z95334;β-Bromo-4-fluorophenetole;4-FLUOROPHENOXY-ETHYLBROMIDE;beta-Bromo-4-fluorophenetole;(P-FLUOROPHENOXY)ETHYLBROMIDE;β-Bromo-4-fluorophenetole >4-(2-BROMOETHOXY)FLUOROBENZENE;2-(4-FLUOROPHENOXY)ETHYL BROMIDE;4-Fluorophenoxy-ethylbromide,95%
CBNumber: CB4110439
Molecular Formula: C8H8BrFO
Formula Weight: 219.05
MOL File: 332-48-9.mol

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1-(2-BROMOETHOXY)-4-FLUOROBENZENE Property

Melting point:: 58-60 °C
Boiling point:: 66°C/0.1mmHg(lit.)
Density: 1.4901 (rough estimate)
refractive index: 1.53-1.532
storage temp.: Storage temp. 2-8°C
form: Liquid After Melting
color: Clear colorless to brownish

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-52-22
Safety Statements: 24/25
HazardClass: IRRITANT
HS Code: 29093090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4376
Product name: β-Bromo-4-fluorophenetole
Purity: >98.0%(GC)
Packaging: 5g
Price: $98
Updated: 2025/07/31

TCI Chemical

Product number: B4376
Product name: β-Bromo-4-fluorophenetole
Purity: >98.0%(GC)
Packaging: 25g
Price: $437
Updated: 2025/07/31

TRC

Product number: B750218
Product name: 1-(2-Bromoethoxy)-4-fluorobenzene
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B750218
Product name: 1-(2-Bromoethoxy)-4-fluorobenzene
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB80836
Product name: 1-(2-Bromoethoxy)-4-fluorobenzene
Packaging: 1g
Price: $60
Updated: 2021/12/16

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1-(2-BROMOETHOXY)-4-FLUOROBENZENE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to brownish liquid after melting

Synthesis

371-41-5

106-93-4

332-48-9

Step 2: 22.5% aqueous sodium hydroxide solution (55 mL) was slowly added to a mixed reaction flask containing 1,2-dibromoethane (112 g, 0.60 mol) and 4-fluorophenol (16.8 g, 0.15 mol). The reaction mixture was heated and stirred under reflux conditions for 5 hours. Subsequently, sodium hydroxide (3.0 g, 75 mmol) was added to the reaction system and heating and stirring were continued under reflux conditions for 5 hours. After completion of the reaction, the reaction solution was cooled to room temperature and extracted three times with dichloromethane (100 mL). The organic layers were combined, dried with anhydrous sodium sulfate and the solvent was removed by distillation under reduced pressure. The resulting crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=10:1, v/v) to afford 1-(2-bromoethoxy)-4-fluorobenzene (compound-03) (29.7 g, 0.136 mol, 90% yield).

References

[1] Patent: EP2357165, 2011, A1. Location in patent: Page/Page column 18
[2] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 4, p. 495 - 500
[3] Russian Journal of Organic Chemistry, 2000, vol. 36, # 2, p. 254 - 257
[4] Archiv der Pharmazie, 2013, vol. 346, # 3, p. 180 - 188
[5] European Journal of Medicinal Chemistry, 1992, vol. 27, # 5, p. 545 - 549

1-(2-BROMOETHOXY)-4-FLUOROBENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-BROMOETHOXY)-4-FLUOROBENZENE Suppliers

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332-48-9, 1-(2-BROMOETHOXY)-4-FLUOROBENZENERelated Search:

1-(2-bromoethoxy)-3-fluorobenzene 1-(2-BROMOETHOXY)-2-FLUOROBENZENE 2-(PENTAFLUOROPHENOXY)ETHYL BROMIDE 2-Phenoxyethylbromide 2-bromo-1-(2-bromoethoxy)-4-fluorobenzene 1-(2-bromoethoxy)-2,4-difluorobenzene 4-Fluorophenetole 1-(2-BROMOETHOXY)-4-FLUOROBENZENE

ASISCHEM Z95334

AKOS BC-2656

4-FLUOROPHENOXY-ETHYLBROMIDE

4-(2-BROMOETHOXY)FLUOROBENZENE

2-(4-FLUOROPHENOXY)ETHYL BROMIDE

1-BROMO-2-(4'-FLUOROPHENOXY)ETHANE

1-(2-BROMOETHOXY)-4-FLUOROBENZENE

(P-FLUOROPHENOXY)ETHYLBROMIDE

p-Fluorophenoxy-ethylbromide 95%

4-Fluorophenoxy-ethylbromide,95%

2-(4-Fluorophenoxy)benthyl Bromide

4-(2-Bromoethoxy)fluorobenzene, 1-(2-Bromoethoxy)-4-fluorobenzene, 2-Bromoethyl 4-fluorophenyl ether

beta-Bromo-4-fluorophenetole

4-Fluorophenoxy-ethylbroMide, 95% 25GR

β-Bromo-4-fluorophenetole

1-(2-BroMoethoxy)-4-fluorobenzene, 97+%

β-Bromo-4-fluorophenetole &gt

Benzene, 1-(2-bromoethoxy)-4-fluoro-

2-Bromoethyl 4-Fluorophenyl Ether

332-48-9

Anisoles, Alkyloxy Compounds & Phenylacetates

Bromine Compounds

Fluorine Compounds