N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

Product Name: N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
CAS No.: 519178-28-0
Chemical Name: N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
Synonyms: TNP;IP6K Inhibitor;IP3K Inhibitor;TNP >=95% (HPLC);IP6K1 inhibitor TNP;IP6K1 inhibitor TNP (TNP);IP6K Inhibitor - CAS 519178-28-0 - Calbiochem;N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
CBNumber: CB41128943
Molecular Formula: C20H16F3N7O2
Formula Weight: 443.38
MOL File: 519178-28-0.mol

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N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Property

Boiling point:: 723.4±70.0 °C(Predicted)
Density: 1.543±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥10mg/mL
pka: 10.51±0.10(Predicted)
form: Yellow solid
color: yellow

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Safety

Hazard Codes: T
Risk Statements: 25-36
Safety Statements: 26-45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T3955
Product name: TNP
Purity: ≥95% (HPLC)
Packaging: 5mg
Price: $132.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: T3955
Product name: TNP
Purity: ≥95% (HPLC)
Packaging: 25mg
Price: $683
Updated: 2024/03/01

Sigma-Aldrich

Product number: 406170
Product name: IP6K Inhibitor - CAS 519178-28-0 - Calbiochem
Purity: The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.
Packaging: 5mg
Price: $216
Updated: 2024/03/01

Cayman Chemical

Product number: 21189
Product name: TNP
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 21189
Product name: TNP
Purity: ≥98%
Packaging: 5mg
Price: $143
Updated: 2024/03/01

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N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Chemical Properties,Usage,Production

Uses

TNP provides a means of selectively and rapidly modulating cellular InsP7 levels in vivo without affecting levels of other inositol phosphates.

Biochem/physiol Actions

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

storage

Store at +4°C

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

METOXADIAZONE

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N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Suppliers

China 43 United Kingdom 1 United States 7 USA 1 Global 52

Sigma-Aldrich

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519178-28-0, N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamineRelated Search:

TNP2 (B-2) 2',3'-O-(2,4,6-TRINITROPHENYL) ADENOSINE 5'-TRIPHOSPHATE MONOLITHIUM TRISODIUM SALT TNP-LPS (Lipopolysaccharide) Giemsa stain

IP6K1 inhibitor TNP (TNP)

IP6K Inhibitor - CAS 519178-28-0 - Calbiochem

TNP

N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine

IP3K Inhibitor

IP6K Inhibitor

9H-Purine-2,6-diamine, N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-

TNP >=95% (HPLC)

IP6K1 inhibitor TNP

519178-28-0

C20H16F3N7O2