ChemicalBook > CAS DataBase List > N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

Product Name
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
CAS No.
519178-28-0
Chemical Name
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
Synonyms
TNP;IP6K Inhibitor;IP3K Inhibitor;TNP >=95% (HPLC);IP6K1 inhibitor TNP;IP6K1 inhibitor TNP (TNP);IP6K Inhibitor - CAS 519178-28-0 - Calbiochem;N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine;N6-(4-Nitrobenzyl)-N2-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine
CBNumber
CB41128943
Molecular Formula
C20H16F3N7O2
Formula Weight
443.38
MOL File
519178-28-0.mol
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N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Property

Boiling point:
723.4±70.0 °C(Predicted)
Density 
1.543±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: ≥10mg/mL
pka
10.51±0.10(Predicted)
form 
Yellow solid
color 
yellow
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Safety

Hazard Codes 
T
Risk Statements 
25-36
Safety Statements 
26-45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3955
Product name
TNP
Purity
≥95% (HPLC)
Packaging
5mg
Price
$132.6
Updated
2024/03/01
Sigma-Aldrich
Product number
T3955
Product name
TNP
Purity
≥95% (HPLC)
Packaging
25mg
Price
$683
Updated
2024/03/01
Sigma-Aldrich
Product number
406170
Product name
IP6K Inhibitor - CAS 519178-28-0 - Calbiochem
Purity
The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.
Packaging
5mg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
21189
Product name
TNP
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
21189
Product name
TNP
Purity
≥98%
Packaging
5mg
Price
$143
Updated
2024/03/01
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N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Chemical Properties,Usage,Production

Uses

TNP provides a means of selectively and rapidly modulating cellular InsP7 levels in vivo without affecting levels of other inositol phosphates.

Biochem/physiol Actions

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

storage

Store at +4°C

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine Suppliers

EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
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Aladdin Scientific
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sales@aladdinsci.com
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ApexBio Technology
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United States
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Cayman Chemical Company
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cayman@caymanchem.com
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United States
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MedChemExpress
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Riedel-de Haen AG
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519178-28-0, N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamineRelated Search:


  • IP6K1 inhibitor TNP (TNP)
  • IP6K Inhibitor - CAS 519178-28-0 - Calbiochem
  • TNP
  • N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine
  • N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
  • N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine
  • IP3K Inhibitor
  • IP6K Inhibitor
  • 9H-Purine-2,6-diamine, N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-
  • TNP >=95% (HPLC)
  • IP6K1 inhibitor TNP
  • N6-(4-Nitrobenzyl)-N2-(3-(trifluoromethyl)benzyl)-9H-purine-2,6-diamine
  • 519178-28-0
  • C20H16F3N7O2