5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Product Name: 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
CAS No.: 452105-33-8
Chemical Name: 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
Synonyms: Sunitinib Malate 1;Sunitinib Carbaxylic Acid;Sunitinib Process Impurity 1;Sunitinib Carboxylic Acid Impurity;5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid;5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid;5-[(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxylic Acid;1H-Pyrrole-3-carboxylic acid, 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-;5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid;5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3carboxylic Acid,5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 carboxylic Acid
CBNumber: CB41175932
Molecular Formula: C16H13FN2O3
Formula Weight: 300.2844232
MOL File: 452105-33-8.mol

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5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Property

Melting point:: >295°C (dec.)
Boiling point:: 588.4±50.0 °C(Predicted)
Density: 1.454±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 6.04±0.50(Predicted)
color: Yellow to Dark Red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: F595150
Product name: 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicAcid
Packaging: 50mg
Price: $285
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0105002
Product name: 5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 25MG
Price: $721.88
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 10325
Product name: 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylicAcid
Packaging: 25mg
Price: $875
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0105002
Product name: 5-(5-FLUORO-2-OXO-1,2-DIHYDRO-INDOL-3-YLIDENEMETHYL)-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 250MG
Price: $1732.5
Updated: 2021/12/16

AvaChem

Product number: 2596
Product name: 5-(5-Fluoro-2-oxoindolin-3-ylidene)methyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Packaging: 1g
Price: $650
Updated: 2021/12/16

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5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Chemical Properties,Usage,Production

Uses

Sunitinib intermediate.

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid Suppliers

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452105-33-8, 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic AcidRelated Search:

Sunitinib Impurity 58 Sunitinib Impurity 2 Sunitinib Impurity 18 N-(2-AMinoethyl)-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxaMide Hydrochloride N,N-Dimethyl Sunitinib 3-(DIETHYLAMINO)PROPANAMIDE 1H-Pyrrole-3-carboxamide, N,N-diethyl-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- Sunitinib Impurity 21 Sunitinib Impurity 1 Sunitinib Impurity 23 Sunitinib Impurity 14 Pyrrole-2,4-dicarboxaldehyde, 3,5-dimethyl- (6CI,7CI,8CI) 1H-Pyrrole-3-carboxamide, N-[2-(dimethylamino)ethyl]-5-formyl-2,4-dimethyl- Sunitinib N-Oxide (Z)-ethyl 5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylate N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide N-Desethyl Sunitinib Sunitinib Impurity 4

5-[(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-carboxylic Acid

Sunitinib Malate 1

5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Sunitinib Carboxylic Acid Impurity

1H-Pyrrole-3-carboxylic acid, 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-

5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid

5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3carboxylic Acid,5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 carboxylic Acid

Sunitinib Carbaxylic Acid

5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Sunitinib Process Impurity 1

452105-33-8

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